In Vitro Antinephrolithiasis Effect of Breadfruit (Artocarpus Altilis (Park) Fosberg) Leaf Extract by Atomic Absorption Spectrophotometry

Abstract

Objective: The objective of this study is to observe the solubility calcium oxalate as a prototype of kidney stone in breadfruit leaf extract solution (n-hexane extract solution, ethyl acetate extract solution, and ethanol extract solution) by atomic absorption spectrophotometry.Methods: Research was conducted qualitatively to analyze calcium oxalate solubility in breadfruit leaf extract solution. The solubility of calcium was known by measuring the levels of calcium in extract solution before and after incubation with calcium oxalate. Potassium as a factor that can enhance the solubility of calcium oxalate also measured by atomic absorption spectrophotometry.Results: The higher concentration of extract solution used in incubation with calciumoxalate, the higher dissolving activity of calcium oxalate. The highest activity was found in ethyl acetate extract to dissolve calcium oxalate. Potassium has a small effect on the activity of dissolving calcium oxalate. Activity may be due to the phytochemical content present in the ethyl acetate extract.Conclusion: Ethyl acetate extract solution has the highest activity to dissolve calcium compared to n-hexane extract and ethanol extract solution.

In Vitro Test of Anticalculi Effect from Ethyl Acetate Fraction of Chives Leaf (Allium schoenoprasum L.)

“…From the calibration curve measurements (Figure 1), the regression Y=0.101443X+0.000795 was obtained. The calcium correlation cofficient obtained could be accepted according to Harmita (2004) and Putra et al (2018) [10], [11], [12].…”

Hepatoprotective Activity of Vernonia Amygdalina Leaf Ethanolic Extract in White Rats Induced by Paracetamol

“…Several phytochemical extracts have been tested for the anticonvulsan [4], antinephrolitiatic [5,6], antibacterial [7,8], antioxidant [8][9][10][11], antidiabetic [12], antimalarial [13,14], anticancer [14][15][16], and antihepatotoxicity [17] activities. Some medicinal plants that have been researched and recognized as hepatoprotective are turmeric and ginger [18].…”