In Vitro Antioxidant Activity and HPTLC Analysis of Borago officinalis Linn.

Singh, Mhaveer; Kamal, Y. T.; Khan, Mubarak Ali; Parveen, Rabea; Ahmad, Sayeed

doi:10.5530/ijper.47.4.4

Cited by 5 publications

(3 citation statements)

References 15 publications

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“…Bandoniene and Murkovic (2002) [67] used HPLC-DPPH to detect radical-scavenging compounds in the hydromethanolic extract, with antioxidant capacity mainly attributed to rosmarinic acid (15.8 mg/g dry matter). García-Iñiguez-de-Ciriano et al (2009) [70] explored the radical scavenging properties of an aqueous [68] conducted antioxidant tests on various leaf extracts (i. e., methanol, chloroform, and petroleum ether). The methanolic extract demonstrated superior DPPH and nitric oxide scavenging activities compared to the others.…”

Section: Antioxidant Activity Of B Officinalis Leavesmentioning

confidence: 99%

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Borago Officinalis L.: A Review Oon Extraction, Phytochemical, and Pharmacological Activities

Slama,

Slougui,

Benaissa

et al. 2024

Chemistry & Biodiversity

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Borago officinalis L., an annual herb belonging to the Boraginaceae family, is used in the traditional medical practices of various countries and for multiple treatments, including respiratory disorders, colds, influenza, diarrhea, cramps, inflammation, palpitation, hypertension menopause, and post‐menopausal symptoms. Its pharmacological properties and biological activities ‐ among them antioxidant, antimicrobial, anticancer, anti‐inflammatory, insecticidal, antigenotoxic, and anti‐obesity activity ‐ were demonstrated in vitro and in vivo and are related to its rich content of bioactive compounds (mainly phenolic acids, flavonoids, anthocyanins, alkaloids, and terpenes) extracted from various parts of B. officinalis including leaves, flowers, seeds, and roots. This review summarizes all updated information on applied extraction processes, phytochemistry, pharmacology, and toxicity of B. officinalis.

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Section: Antioxidant Activity Of B Officinalis Leavesmentioning

confidence: 99%

“…Singh et al. (2014) [68] conducted antioxidant tests on various leaf extracts (i. e., methanol, chloroform, and petroleum ether). The methanolic extract demonstrated superior DPPH and nitric oxide scavenging activities compared to the others.…”

Section: Biological and Pharmacological Activitiesmentioning

confidence: 99%

Borago Officinalis L.: A Review Oon Extraction, Phytochemical, and Pharmacological Activities

Slama,

Slougui,

Benaissa

et al. 2024

Chemistry & Biodiversity

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show abstract

“…Several metabolites were reported including resins, tannins, ascorbic acid, niacin, betacarotene, riboflavin, silicic acid, thiamine, choline arabinose, polyphenolics, and unsaturated pyrrolizidine alkaloids (amabiline, lycopsamine and supinidine) (8,(22)(23)(24)(25) .…”

Section: Chemical Compositionmentioning

confidence: 99%

Pharmacological aspects of Borago officinalis (Borage): A review article

Ibrahim

Alshammaa

2023

IJPS

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Abstract: Borago officinalis is highly interesting amongst nutritional and medical source relate to its high composition of some useful phytochemical compound. It is great plants with bright blue star-shaped flowers present in most world regions and usually known as borage. The Borago phytochemical analysis showed the presence of alkaloids, tannins, flavonoids, phenolic acids, essential oil, vitamins and others. Borage is cultivated all over the world and used in traditional medicine as a demulcent, diuretic, emollient, tonic, expectorant, for the treatment of coughs, inflammation and swelling, and other diseases. In herbal medicine, Borage seed oil (BSO) has been utilized for many progressive illnesses as a treatment agent. The BSO compounds include p-simen-8-L, ?-caryophyllene, sesquiterpenes, monoterpenes, alpha-linoleic, gammalinoleic and linoleic acid. BSO is famed to be the richest vegetable origin of gamma (?)-linoleic acid (GLA). Borage officinalis possess different pharmacological properties including antinociceptive, antioxidant, radioprotective, memory improving, hepatoprotective, antinflammatory, and analgesic effects.

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A Validated, Rapid and Cost-Efficient HPTLC Method for Quantification of Gamma-Linolenic Acid in Borage Oil and Evaluation of Antioxidant Activity

Kawish

Qadir

Saad

et al. 2021

Journal of Chromatographic Science

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Borage oil that is extracted from (Borago officinalis Linn.) is a well-known medicinal plant having various medicinal benefits. In this work, an affordable, simple, reliable, rapid and easily accessible high-performance thin-layer chromatography (HPTLC) method was developed for the estimation of gamma-linolenic acid (GLA) in borage oil. HPTLC method employs thin-layer chromatography (TLC) aluminum plates precoated with silica gel (G60F254) as the stationary phase, and the mixture of hexane:toulene:glacial acetic acid (3:7:1, v/v/v) was used as the mobile phase. Densitometric analysis of the TLC plates was carried out at 200 nm. The developed method showed well-resolved spots with retention factor (Rf) value of 0.53 ± 0.04 for GLA. Various experimental conditions like saturation time for chamber, solvent phase migration and width of the band were studied intensely for selecting the optimum conditions. The method validation was performed for parameters like linearity, accuracy, specificity and precision. The values of limit of detection and limit of quantification for GLA were found to be 0.221 and 0.737 μg/band, respectively. In nutshell, the developed HPTLC method was found to be highly sensitive for the estimation of GLA in the herbal oil samples and formulations.

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In Vitro Antioxidant Activity and HPTLC Analysis of Borago officinalis Linn.

Cited by 5 publications

References 15 publications

Borago Officinalis L.: A Review Oon Extraction, Phytochemical, and Pharmacological Activities

Borago Officinalis L.: A Review Oon Extraction, Phytochemical, and Pharmacological Activities

Pharmacological aspects of Borago officinalis (Borage): A review article

A Validated, Rapid and Cost-Efficient HPTLC Method for Quantification of Gamma-Linolenic Acid in Borage Oil and Evaluation of Antioxidant Activity

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