In vitro correlation studies of antidiabetic, antioxidant activity and HPLC-ESI-MS/MS analysis of marine seaweeds from Gulf of Mannar

Maheswari,; D.E., Salamun

doi:10.1016/j.rsma.2022.102682

Cited by 3 publications

(3 citation statements)

References 29 publications

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“…According to Maheswari and Salamun. [68] the highest ABTS radical scavenging activity (96.95 ± 0.41%) was observed in C. verticillata than standard ascorbic acid (90.99 ± 0.30%). Mani et al [69] evaluated the antioxidant potential of various species of tropical green seaweeds, in which C. antennia showed higher ABTS activity (IC 50 0.93 mg/mL).…”

Section: Abts Activitymentioning

confidence: 86%

“…According to Maheswari and Salamun. [68] the highest ABTS radical scavenging activity (96.95 ± 0.41%)…”

Section: Dpph Activitymentioning

confidence: 96%

“…macrophysa showed 60% of DPPH scavenging activity. The decolorization of bluish-green ABTS due to polyphenolic compounds present in algal extracts was measured at 734 nm to determine the ABTS activity [68]. Similar to DPPH activity, ABTS also performed in a dose-dependent manner.…”

Section: Dpph Activitymentioning

confidence: 99%

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Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

et al. 2023

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Exploration of seaweeds to unravel their bioactive metabolites from the perspective of wider applications gained substantial importance. The present study was performed to investigate the total phenolic, flavonoid, tannin content, antioxidant activity and antibacterial potential of various solvent extracts of green seaweed Caulerpa racemosa. The methanolic extract showed higher phenolic (11.99 ± 0.48 mg gallic acid equivalents/g), tannin (18.59 ± 0.54 mg tannic acid equivalents/g) and flavonoid (33.17 ± 0.76 mg quercetin equivalents/g) content than other extracts. Antioxidant activity was determined by using 2,2-diphenylpicrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay with different concentrations of C. racemosa extracts. The methanolic extract showed higher scavenging potential in both the DPPH and ABTS activity with the inhibition value of 54.21 ± 1.39% and 76.62 ± 1.08%, respectively. Bioactive profiling was also identified by using Gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared (FT-IR) techniques. These studies revealed the presence of valuable bioactive compounds in C. racemosa extracts and these compounds might be responsible for antimicrobial, antioxidant, anticancer and anti-mutagenic properties. Major compounds identified in GC-MS were 3,7,11,15-Tetramethyl-2-hexadecen-1-ol, 3-hexadecene and Phthalic acid. In terms of antibacterial activity, C. racemosa has promising antibacterial potential against aquatic pathogens Aeromonas hydrophila, Aeromonas veronii and Aeromonas salmonicida. Further evaluation studies focusing aquatic related aspects would reveal the novel bioproperties and applications of C. racemosa.

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Section: Abts Activitymentioning

confidence: 86%

“…According to Maheswari and Salamun. [68] the highest ABTS radical scavenging activity (96.95 ± 0.41%)…”

Section: Dpph Activitymentioning

confidence: 96%

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Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

et al. 2023

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Review of the pharmacological properties of marine macroalgae used in the treatment of diabetes mellitus in Indonesia

Samudra,

Nugroho,

Murwanti

2024

Annales Pharmaceutiques Françaises

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Comparison of Chemical Composition and Bioactivities of Polysaccharides of Brown Seaweeds, the Red Sea, Egypt, Hurghada

Ismail,

Ibrahim,

El Zokm

2024

Hydrob J

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Sulfated polysaccharides (SPs) from algae have been shown to be effective in a number of biological applications. Therefore, the chemical composition and different biological functions of various SPs were determined for three brown seaweed species from the Egyptian Red Sea: Dictyopteris polypodioides, Polycladia myrica, and Turbinaria decurrens. It has been found that the yield of crude SPs was higher than that of alginate and fucoidan with a range of 43.64% to 61.90%. Fucoidan, which has the maximum carbohydrate content of 56.89%, was found in D. polypodioides. The crude SPs of P. myrica had the greatest sulfate content of 22.44%. All functional groups of the examined samples were confirmed by the Fourier Transform Infrared spectrum (FTIR). Experimentally, three applicable assays were used to quantify the antioxidant activity of the extracted SPs depending on the method used, the type of polysaccharides, and algal species. The anti-diabetic activity of T. decurrens-crude SPs was highly active scoring 85.85% in the α-glucosidase assay. The anti-obesity activity showed the highest value (95.25%) for T. decurrens-fucoidan. Besides, T. decurrens-crude SPs showed the highest anti-arthritic activity (89.89%). In addition, a few positive records of antibacterial activity were detected. Furthermore, the most potent T. decurrens-crude SPs extract was tested for cytotoxicity against human liver cells and found to be safe. The activity of the isolated SPs and their chemical composition were shown to be correlated. Conclusively, the bioactivities recorded herein by the tested SPs pose promising medicinal applications towards developing a new therapeutic intervention.

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In vitro correlation studies of antidiabetic, antioxidant activity and HPLC-ESI-MS/MS analysis of marine seaweeds from Gulf of Mannar

Cited by 3 publications

References 29 publications

Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

Evaluation of Phytochemical Screening, Pigment Content, In Vitro Antioxidant, Antibacterial Potential and GC-MS Metabolite Profiling of Green Seaweed Caulerpa racemosa

Review of the pharmacological properties of marine macroalgae used in the treatment of diabetes mellitus in Indonesia

Comparison of Chemical Composition and Bioactivities of Polysaccharides of Brown Seaweeds, the Red Sea, Egypt, Hurghada

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