In vitro effects of a fraction separated from Polygonum cuspidatum root on the viability, in suspension and biofilms, and biofilm formation of mutans streptococci

Anti-biofilm activity ofSalvadora persicaon cariogenic isolates ofStreptococcus mutans:in vitroand molecular docking studies

“…GC-MS of S. persica methanol extracts revealed a large number of phytochemicals comprising many groups (although most were phenolic). Although numerous bioactive substances have been isolated from plants and their modes of action investigated, relatively few studies have been done in dental research (Song et al 2007). In general, it is recognized that plant polyphenols bind strongly to proteins through reversible interactions.…”

In vitro antimicrobial activity of Caesalpinia ferrea Martius fruits against oral pathogens

“…This is also valid for Brazilian medicinal plants when evaluated as oral antimicrobials (Vasconcelos et al, 2006). The understanding of oral ecological imbalances in microbial biofilms are of great importance to develop strategies to prevent dental caries and periodontal diseases since oral microorganisms organized in biofilms are more resistant to immune defense mechanisms and less susceptible to chemical agents (Davies, 2003;Marsh, 2006;Song et al, 2007;Quave et al, 2008). Therefore, the MIC reference values (end points) are useful, but these data must be taken with caution when considering biofilm related oral diseases.…”

Separation of an effective fraction from turmeric against Streptococcus mutans biofilms by the comparison of curcuminoid content and anti-acidogenic activity

“…ME and its fractions were stored at À20°C until tested. The MICs of ME and its fractions were determined using a micro dilution method, as described by Song et al (2007). Inoculum suspensions were prepared from 18-24 h broth cultures.…”