In vitro effects on mobile polyethylene insert under highly demanding daily activities: stair climbing

Jaber, Sami Abdel; Taddei, Paola; Tozzi, Silvia; Sudanese, A; Affatato, Saverio

doi:10.1007/s00264-014-2622-5

Cited by 17 publications

(11 citation statements)

References 41 publications

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“…Loading on knee joint primarily depends on the physical activity and body weight (BW). The high variability of loads, according to the anthropometric features specific to each subject, is observed from several studies [6,12,13,15,16]. These studies also point out that different people, with similar weight and height, show different load configurations due to their different ways to run specific movements.…”

Section: Discussionmentioning

confidence: 95%

“…A complex morphometric relation characterizes the knee and currently at the authors’ knowledge, there are no studies about the combined effect of patient weight and load applied on the knee. An in vivo performance of knee prostheses, according to the relation between patient body mass index (BMI) and load applied, showed high variability of load according to the anthropometric features specific to each subject [6,12,13,15,16]. These studies, performed on different people with similar weight and height, showed different load configurations due to the different ways in which anyone runs a specific movement.…”

Section: Discussionmentioning

confidence: 99%

“…Our study focused on outlining a consistent protocol for DC knee wear simulation under the standard [34,35] and “high-demanding-activity” conditions [11,12], integrating a musculoskeletal multibody loads calculation procedure using different load profiles calculated from real life activities kinematical data in order to predict and reduce knee wear phenomena. Furthermore, the knowledge of the more realistic load profiles acting on the joint during walking gives the opportunity to investigate in an accurate way on the unsteady lubricating phenomena acting in the tribosystems by using novel lubrication models [36,37].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the research is exploring more accurate methods of analysis that allow for movements and loads acting on knee joint to be obtained. Some authors have focused on the analysis of loads acting on the knee joint for different activities, such as level walking, climbing stairs, or running, in order to estimate a more realistic load profile and thereby, obtain a more realistic behavior of the artificial knee joints during wear simulations [11,12,13,14,15]. Bergman et al [14] focused on knee joint kinetics, using a transducer, installed inside the implanted prosthesis on the human subject, which measures the forces and moments acting on knee during different in vivo motion conditions.…”

Section: Introductionmentioning

confidence: 99%

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A Critical Analysis of TKR In Vitro Wear Tests Considering Predicted Knee Joint Loads

Affatato

Ruggiero

2019

Materials

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Detailed knowledge about loading of the knee joint is essential for preclinical testing of total knee replacement. Direct measurement of joint reaction forces is generally not feasible in a clinical setting; non-invasive methods based on musculoskeletal modelling should therefore be considered as a valid alternative to the standards guidelines. The aim of this paper is to investigate the possibility of using knee joint forces calculated through musculoskeletal modelling software for developing an in vitro wear assessment protocol by using a knee wear simulator. In particular, in this work we preliminarily show a comparison of the predicted knee joint forces (in silico) during the gait with those obtained from the ISO 14243-1/3 and with those measured in vivo by other authors. Subsequently, we compare the wear results obtained from a knee wear joint simulator loaded by calculated forces in correspondence to the “normal gait” kinematics with those obtained in correspondence to the loads imposed by the ISO. The obtained results show that even if the predicted load profiles are not totally in good agreement with the loads deriving from ISO standards and from in vivo measurements, they can be useful for in vitro wear tests, since the results obtained from the simulator in terms of wear are in agreement with the literature data.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Critical Analysis of TKR In Vitro Wear Tests Considering Predicted Knee Joint Loads

Affatato

Ruggiero

2019

Materials

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“…The so-called “patient’s daily activities” have to be considered as a worst-case scenario for testing, as well as for implant design. To cover these lacunae, based on previous studies [16,19,20], these experiences were translated to the hip simulator.…”

Section: Introductionmentioning

confidence: 99%

Quantification of Wear and Deformation in Different Configurations of Polyethylene Acetabular Cups Using Micro X-ray Computed Tomography

2017

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Wear is currently quantified as mass loss of the bearing materials measured using gravimetric methods. However, this method does not provide other information, such as volumetric loss or surface deviation. In this work, we validated a technique to quantify polyethylene wear in three different batches of ultrahigh-molecular-polyethylene acetabular cups used for hip implants using nondestructive microcomputed tomography. Three different configurations of polyethylene acetabular cups, previously tested under the ISO 14242 parameters, were tested on a hip simulator for an additional 2 million cycles using a modified ISO 14242 load waveform. In this context, a new approach was proposed in order to simulate, on a hip joint simulator, high-demand activities. In addition, the effects of these activities were analyzed in terms of wear and deformations of those polyethylenes by means of gravimetric method and micro X-ray computed tomography. In particular, while the gravimetric method was used for weight loss assessment, microcomputed tomography allowed for acquisition of additional quantitative information about the evolution of local wear and deformation through three-dimensional surface deviation maps for the entire cups’ surface. Experimental results showed that the wear and deformation behavior of these materials change according to different mechanical simulations.

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Comparative micro‐Raman study on standard, cross‐linked and vitamin E‐blended polyethylene acetabular cups after long‐term in vitro testing and ageing

Taddei

Pavoni

Affatato

2017

J Raman Spectroscopy

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Ultra‐high molecular‐weight polyethylene has been used in total joint replacement for the last three decades. Many attempts have been made to improve the wear behaviour of this material. Highly cross‐linked polyethylene (XLPE) has been developed to decrease the wear rate, while the addition of stabilizers such as vitamin E has been proposed to slow the oxidation processes. In this study, we compared the wear behaviour of conventional ultra‐high molecular‐weight polyethylene, XLPE and vitamin E‐added XLPE acetabular cups for total hip arthroplasty. The samples were run for five million cycles on a hip joint simulator (first test), then underwent an accelerated ageing treatment, were tested again for two million cycles (second test) and finally were run for another two million cycles in presence of third‐body particles (third test). Our study showed that vitamin E‐added XLPE cups had a better wear behaviour only in the long‐term and more severe testing conditions: in the third test, they underwent the lowest increase in wear rate. Micro‐Raman spectroscopy allowed us to analyse the wear degradation of the cups on a molecular scale, and differences in the wear mechanisms were revealed. The presence of vitamin E did not prevent structural changes upon the first test, while it did in ageing and in the second test. In the third test, more significant structural changes were observed; the XLPE cups, which lost the lowest mass, had the most modified articular surface. These morphological aspects should be taken into account, together with gravimetric wear rates, in the characterization of wear degradation. Copyright © 2017 John Wiley & Sons, Ltd.

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In vitro effects on mobile polyethylene insert under highly demanding daily activities: stair climbing

Cited by 17 publications

References 41 publications

A Critical Analysis of TKR In Vitro Wear Tests Considering Predicted Knee Joint Loads

A Critical Analysis of TKR In Vitro Wear Tests Considering Predicted Knee Joint Loads

Quantification of Wear and Deformation in Different Configurations of Polyethylene Acetabular Cups Using Micro X-ray Computed Tomography

Comparative micro‐Raman study on standard, cross‐linked and vitamin E‐blended polyethylene acetabular cups after long‐term in vitro testing and ageing

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