In vitro fertilization: an unexpected finding in a cohort of patients with biliary atresia

Costa, Carolina Magalhães; Porta, Adriana; Miura, Irene Kazue; Porta, Gilda; Fonseca, Eduardo A.; Pugliese, Renata; Kondo, Mário; Chapchap, P; Sindhi, Rakesh; Feier, Flávia Heinz; Neto, João Seda

doi:10.1590/1414-431x2023e12671

Cited by 2 publications

(1 citation statement)

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“…To date, no air embolism complication during a living-donor liver transplantation procedure has been reported in pediatric patients with biliary atresia. However, congenital heart disease and biliary atresia were unexpected prevalent associations in several cohorts (10)(11)(12). A contemporary cohort study demonstrated liver transplantation recipients with biliary atresia may have an associated diagnosis of congenital heart disease at a rate of 16.4% (13).…”

Section: Discussionmentioning

confidence: 99%

A 7-month-old girl with a suspected air embolism complication during a living-donor liver transplantation procedure: a case report

Huang,

Yang,

et al. 2023

Front. Pediatr.

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BackgroundPediatric liver transplantation is an important modality for treating biliary atresia. The overall survival rate of pediatric liver transplantation has significantly improved. The incidence of perioperative cardiac events was evaluated, and risk factors were also investigated in adult patients undergoing liver transplantation in previous studies. To the best of our knowledge, this is the first case of a cardiac event during a pediatric living-donor liver transplantation.Case summaryOur report describes the management of cardiac events during a liver transplantation in a 7-month-old girl. The ST segment began to increase to 3.0 mm immediately after reperfusion, with peak ST-segment elevation reaching 13.2 mm after 45 min. The procedure ended uneventfully after continuous symptomatic and etiological treatment. It was considered to be the occurrence of an acute air embolism complication during the procedure based on the electrocardiograph and biomarkers. An echocardiogram during follow-up showed a patent foramen ovale with a left-to-right shunt tract width of 2.7 mm.DiscussionPediatric liver transplantation has become a state-of-the-art treatment for children with end-stage liver disease and can improve the quality of life to some extent. These children may be complicated with congenital heart disease, which increases the risk of surgery. Application of echocardiogram, close monitoring, and appropriate management may reduce the incidence of perioperative cardiac events.

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