In vitro mycotoxin binding capacities of clays, glucomannan and their combinations

Oguz, H.; Bahcivan, Emre; Erdoğan, Teslime; Yalçın, Nihayet Fadime; Ozdas, Ayse; Işık, Mehmet; Altunbaş, Osman

doi:10.1016/j.toxicon.2022.05.006

Cited by 9 publications

(10 citation statements)

References 43 publications

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“…In this regard, glucomannan, mannoprotein, chitin, and β-glucan content in the yeast cell wall can act as bioadsorbents for mycotoxins (Figure ). , Most studies employed heat-inactivated or live yeast cells for the bioadsorption of mycotoxins (Table ). …”

Section: Biodetoxification Of Mycotoxinsmentioning

confidence: 99%

Recent Insights into the Use of Antagonistic Yeasts for Sustainable Biomanagement of Postharvest Pathogenic and Mycotoxigenic Fungi in Fruits with Their Prevention Strategies against Mycotoxins

Öztekin

Dikmetaş

Devecioglu

et al. 2023

J. Agric. Food Chem.

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Fungi-induced postharvest diseases are the leading causes of food loss and waste. In this context, fruit decay can be directly attributed to phytopathogenic and/or mycotoxin-producing fungi. The U.N. Sustainable Development Goals aim to end hunger by 2030 by improving food security, sustainable agriculture, and food production systems. Antagonistic yeasts are one of the methods presented to achieve these goals. Unlike physical and chemical methods, harnessing antagonistic yeasts as a biological method controls the decay caused by fungi and adsorbs and/or degrades mycotoxins sustainably. Therefore, antagonistic yeasts and their antifungal mechanisms have gained importance. Additionally, mycotoxins’ biodetoxification is carried out due to the occurrence of mycotoxin-producing fungal species in fruits. Combinations with processes and agents have been investigated to increase antagonistic yeasts’ efficiency. Therefore, this review provides a comprehensive summary of studies on preventing phytopathogenic and mycotoxigenic fungi and their mycotoxins in fruits, as well as biocontrolling and biodetoxification mechanisms.

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Section: Biodetoxification Of Mycotoxinsmentioning

confidence: 99%

Recent Insights into the Use of Antagonistic Yeasts for Sustainable Biomanagement of Postharvest Pathogenic and Mycotoxigenic Fungi in Fruits with Their Prevention Strategies against Mycotoxins

Öztekin

Dikmetaş

Devecioglu

et al. 2023

J. Agric. Food Chem.

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“…Adsorption is mainly through the microbial cell wall of glucomannans, mannans, β-glucans, and other substances to play a role in DON detoxification. In vitro studies have reported that glucomannan bound DON at a median rate (31%-56%), but the binding capacity can increase by 15%-20% when glucomannan is added in combination with clay (Oguz et al, 2022). Tapingkae et al (2022) have shown that red yeast cells containing high levels of β-glucans have mycotoxins (0.31-2.50 μg/mL) adsorption capacity in vitro and gastrointestinal poultry models.…”

Section: Adsorption and Antagonismmentioning

confidence: 99%

“…Adsorption is mainly through the microbial cell wall of glucomannans, mannans, β‐glucans, and other substances to play a role in DON detoxification. In vitro studies have reported that glucomannan bound DON at a median rate (31%–56%), but the binding capacity can increase by 15%–20% when glucomannan is added in combination with clay (Oguz et al., 2022). Tapingkae et al.…”

Section: Detoxification Mechanisms Of Biological and Nutritional Miti...mentioning

confidence: 99%

Global distribution, toxicity to humans and animals, biodegradation, and nutritional mitigation of deoxynivalenol: A review

Liu

Cai

et al. 2023

Comp Rev Food Sci Food Safe

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Deoxynivalenol (DON) is one of the main types of B trichothecenes, and it causes health‐related issues in humans and animals and imposes considerable challenges to food and feed safety globally each year. This review investigates the global hazards of DON, describes the occurrence of DON in food and feed in different countries, and systematically uncovers the mechanisms of the various toxic effects of DON. For DON pollution, many treatments have been reported on the degradation of DON, and each of the treatments has different degradation efficacies and degrades DON by a distinct mechanism. These treatments include physical, chemical, and biological methods and mitigation strategies. Biodegradation methods include microorganisms, enzymes, and biological antifungal agents, which are of great research significance in food processing because of their high efficiency, low environmental hazards, and drug resistance. And we also reviewed the mechanisms of biodegradation methods of DON, the adsorption and antagonism effects of microorganisms, and the different chemical transformation mechanisms of enzymes. Moreover, nutritional mitigation including common nutrients (amino acids, fatty acids, vitamins, and microelements) and plant extracts was discussed in this review, and the mitigation mechanism of DON toxicity was elaborated from the biochemical point of view. These findings help explore various approaches to achieve the best efficiency and applicability, overcome DON pollution worldwide, ensure the sustainability and safety of food processing, and explore potential therapeutic options with the ability to reduce the deleterious effects of DON in humans and animals.

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“…One of the methods to reduce AFB1 toxicity in poultry is the addition of toxin binders in feed (Zabiulla et al, 2021). Toxin binders are compounds that can bind to mycotoxins in the digestive tract so that these toxic compounds can be excreted through the excreta (Ahlberg et al, 2019;Oguz et al, 2022). The most widely used binder toxins in the poultry world are phyllosilicate, including bentonite, zeolite, montmorillonite, and hydrated sodium calcium aluminosilicate (Rejeb et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Effect of Phyllosilicates As Toxin Binder On Productivity, Intestinal Morphology, and Liver Toxicity in Broiler Fed Afb1 Contaminated Feed

Prahara,

Humaera,

Yusiati

et al. 2023

BuletinPeternak

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Aflatoxin B1 is a toxin produced by the fungus Aspergillus flavus which reduces the development and function of organs in broilers. The aim of this study was to determine the effect of adding binder toxin from different bentonite to feed contaminated with AFB1 on productivity, intestinal morphology, and liver toxicity in broilers. A total of 60-day old chick male broilers were placed in 12 pens. Each treatment consisted of three replicates, each replicate containing five broilers. Treatment in the study consisted of P0 (control, basal diet, without the addition of AFB1), P1 (P0 + 100 µg/kg AFB1 + 4 g/kg calcium bentonite Type A), P2 (P0 + 100 µg/kg AFB1 + 4 g/kg calcium bentonite Type B), and P3 (P0 + 100 µg/kg AFB1 + 4 g/kg calcium bentonite Type B + kerolite + saponite). Treatment diets were given to broilers from day 22 to 35 (finisher phase). The results showed that the toxin binder on AFB1 contaminated feed had no effect on feed consumption, body weight gain and feed conversion (p>0.05). Addition of toxin binder on AFB1 contaminated feed increased the relative weight of the duodenum (p=0.024), although P3 was not significantly different. Treatments had no effect on villus length, crypt depth, and ratio of villus length to crypt depth (p>0.05), but decreased villus width (p=0.013). The addition of toxin binder tended to decrease the villus area (p=0.055). SGOT and SGPT did not show differences between treatments. AFB1 contamination with the addition of toxin binder showed signs of toxicity on liver histopathological observations. Based on the research, it can be concluded that the addition of binder toxin in feed contaminated with AFB1 can reduce the negative effect on the development of intestinal villus and chemical effect to the liver. Toxin binder Type B has the best efficacy for reduce the negative effect

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In vitro mycotoxin binding capacities of clays, glucomannan and their combinations

Cited by 9 publications

References 43 publications

Recent Insights into the Use of Antagonistic Yeasts for Sustainable Biomanagement of Postharvest Pathogenic and Mycotoxigenic Fungi in Fruits with Their Prevention Strategies against Mycotoxins

Recent Insights into the Use of Antagonistic Yeasts for Sustainable Biomanagement of Postharvest Pathogenic and Mycotoxigenic Fungi in Fruits with Their Prevention Strategies against Mycotoxins

Global distribution, toxicity to humans and animals, biodegradation, and nutritional mitigation of deoxynivalenol: A review

Effect of Phyllosilicates As Toxin Binder On Productivity, Intestinal Morphology, and Liver Toxicity in Broiler Fed Afb1 Contaminated Feed

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