Incidence and Risk Factors for Herpes Zoster among Patients with Inflammatory Bowel Disease

Risk of Herpes zoster in patients with psoriasis treated with biologic drugs

“…17 In an extensive search of the literature, only two studies dealing with the incidence of HZ related to biologic drugs among psoriasis patients Herpes zoster, psoriasis and biologics drugs (both limited to treatment with efalizumab) were found. 18,19 Previous studies of the association between biologic drugs and HZ have included patients with rheumatoid arthritis, 12,13,20-23 inflammatory bowel disease 24 or some combination of these diagnoses. 25,26 Langley et al 18 reported that among 2475 patients treated with efalizumab for psoriasis, less than 2% developed HZ.…”

Safety of herpes zoster vaccination among inflammatory bowel disease patients being treated with anti‐TNF medications

“…Among the whole group the median number of follow-ups within 12 months after receiving HZV was 14 (Range 2-51). Seven (11.9%) patients did not have a follow-up within 42 days but during the 12 months after receiving HZV, they had a median of 11 visits (range [3][4][5][6][7][8][9][10][11][12][13][14]. No cases of HZ were found within 42 days of HZV administration.…”

“…The risk of HZ is elevated in patients with inflammatory bowel disease (IBD) who are treated with immunosuppressive medications including anti-TNF medications. 8,9 In addition, the clinical course of HZ is more complicated among patients who develop the disease while on immunosuppressive therapy. 10 However, since HZV is a live vaccine, it is contraindicated in patients who are currently taking anti-TNF medications.…”

Risk factors for herpes zoster in rheumatoid arthritis patients: the role of tumour necrosis factor‐α inhibitors

“…12,13 People with RA have been found to have an increased risk of HZ in comparison with the general population. [14][15][16] An increased risk in people with RA has also been found to be associated with use of glucocorticoids 15,[17][18][19] and some non-biologic disease modifying anti-rheumatic drugs (DMARD) (e.g. leflunomide, cyclophosphamide and azathioprine), 15,19 while exposure to methotrexate has not been found to be associated with an increased risk of HZ.…”