Incidence, endoscopic morphology and distribution of metastatic lesions in the gastrointestinal tract

Abstract

Although metastatic lesions in the GIT are rare, they do occur. They usually present as single and primary carcinoma-like lesions, with the stomach and duodenum most commonly involved.

Rectal Cancer and Anal Sphincter Disorders

“…Such findings are estimated to account for 0.03 % of upper GI endoscopies and 0.05 % of colonoscopies [80]. The EUS appearance without FNA of secondary rectal linitis plastica is that of circumferential wall thickening affecting predominantly the submucosal and muscularis propria layers similar to primary gastric linitis plastica (Fig.…”

Review of clinical and endoscopic features of metastatic tumors of the gastrointestinal tract

“…The presenting symptoms may be nonspecific, although, the symptoms of gastrointestinal bleeding and abdominal pain seem to be the two most common symptoms in most studies. [1,18,19] Occasionally, symptoms of weight loss, dysphagia, [3] dyspepsia, and bowel obstruction [20] may be the presenting complaints. In Taiwanese review of 42 patients, gastrointestinal bleeding was the presenting symptom for about 60% patients while abdominal pain was present in about 19%.…”

“…In Taiwanese review of 42 patients, gastrointestinal bleeding was the presenting symptom for about 60% patients while abdominal pain was present in about 19%. [1] The gastrointestinal bleeding can be gross, occult, acute or chronic. Small bowel palpable mass from metastatic melanoma [20] and obstructive jaundice from metastasis to the ampulla has been reported.…”

“…However, a retrospective review of 42 patients in Taiwan with metastasis to the gastrointestinal tract showed that hepatocellular carcinoma was the leading primary lesion for such metastasis. [1] This led them to speculate that for different countries, differences exist as regards cancer epidemiology, and that the primary cancer most commonly metastasizing to the digestive tract may differ from country to country or ethnicity to ethnicity.…”

“…The reported incidence has been found to be about 1/3847 in upper endoscopic procedures and 1/1871 colonoscopies in one retrospective review of endoscopy database. [1] The other study, based on a questionnaire survey of the staff of 34 medical clinics, demonstrated that the metastasis to the gastrointestinal tract were verified among 3477 upper gastrointestinal endoscopic procedures while no lower gastrointestinal tract metastasis appeared to have been detected from among 1634 colonoscopies. [2] Based on the multiple autopsy studies the incidence of metastatic lesions in the esophagus has been reported to range from 0.3 to 6.1% [3][4][5][6] and in the stomach the incidence ranged from 0.2 to 5.4%.…”