Incidence, management and recurrence rate of acute pancreatitis

Andersson, Roland; Andersson, Bodil; Haraldsen, Pernille; Drewsen, G; Eckerwall, Gunilla

doi:10.1080/00365520410007061

Cited by 108 publications

(63 citation statements)

References 29 publications

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“…Studies on severe acute pancreatitis often involve any episodes of a consecutive number of pancreatitis in individuals admitted for treatment of acute pancreatitis [39], whereas this study only includes patients with first episode acute pancreatitis, which together with the second episode, are the most severe episodes of acute pancreatitis [40]. Moreover, by limiting recruitment of patient to a well-defined urban area; this study gives unique and robust analyses of ICU admittance risks due to first episode acute pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

The Risk Factors of Intensive Care Unit Admittance during First Attack of Acute Pancreatitis

Dale¹,

Omdal²,

Lie³

et al. 2012

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Background: A proportion of patients with acute pancreatitis develop severe organ dysfunction requiring admittance in an intensive care unit. Patient characteristics associated with ICU admittance were evaluated in this consecutive series of patients. Methods: The clinical course of patients with first attack of acute pancreatitis in urban Norway between 01.01.1996 and 31.12.2006 was reviewed. Patient characteristics, comorbidity, pre hospital delay and likely aetiology of acute pancreatitis were analysed as risk factors for ICU admittance. Results: This study includes 565 patients, 299 women and 266 men (p = 0.089), with a median age of 60 years (range: 17 -98). 50 (9%) of the patients were admitted to the ICU. Men were more at risk than women for ICU admittance (OR 2.34; 95% CI: 1.27 -4.32). Patients with alcohol associated pancreatitis (OR 5.94; 95%, CI: 2.61 -13.53), miscellaneous aetiologies (OR: 2.81, 95% CI: 1.02 -7.73) and non-assessed aetiology (OR 2.71, 95%, CI: 1.26 -5.82) were more at risk of ICU admittance than patients with bile stones associated pancreatitis. Pre hospital delay increased the risk of ICU admittance amongst patients with alcohol associated pancreatitis (OR 4.23; 95%, CI: 1.11 -16.18). Two comorbid conditions conveyed increased risk (OR 8.78; 95%,). The case fatality rate was 24% in the ICU and 1.6% in the ward (OR 20.01, 95% CI: 7.71 -51.93). Conclusions: Aetiology of acute pancreatitis, especially alcohol, pre-hospital delay and male gender are associated with increased of risk of ICU admittance and increased fatality rate during first attack of AP.

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Section: Discussionmentioning

confidence: 99%

The Risk Factors of Intensive Care Unit Admittance during First Attack of Acute Pancreatitis

Dale¹,

Omdal²,

Lie³

et al. 2012

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“…Taking the incidence of acute pancreatitis in Sweden into account 15,16 , about 85 % being mild according to the Atlanta classification 14 , the saving for reduction of hospital stay by immediate oral feeding corresponding to about 0.22 million € per million inhabitants (Sweden). It should though be emphasized that earlier discharge from hospital should not be the primary objective per se for health care.…”

Section: Discussionmentioning

confidence: 99%

Immediate oral feeding in patients with mild acute pancreatitis is safe and may accelerate recovery—A randomized clinical study

et al. 2007

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“…Gallstones are the commonest cause of pancreatitis in the developed countries accounting for about 60 % of all cases [4,5]. In Nepal, the exact data are unavailable, but one study has suggested it to be as common as alcoholic pancreatitis, together accounting for about 66 % of all causes [6].…”

Section: Introductionmentioning

confidence: 99%

Acute Biliary Pancreatitis: An Experience in a Tertiary Level Hospital of Nepal

et al. 2012

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Acute Biliary Pancreatitis is one of the commonest forms of pancreatitis in Nepal. Controversies exist as to the most appropriate way of management of these cases. The present study was carried out to evaluate the management and outcome of Acute Biliary Pancreatitis cases in a tertiary level hospital of Nepal. A retrospective analysis of the patients managed with Acute Biliary Pancreatits was done. All patients admitted with the diagnosis of Acute Biliary Pancreatitis over a period of 2 years were included in the study. The variables measured were age, sex, clinical presentation, laboratory investigations, mode of treatment and outcome. A total of 45 cases had Acute Biliary Pancreatitis suggesting a prevalence of 28 %. The mean age was 45±10 year. 39 patients (86.6 %) were treated with conservative management. 23 patients (54 %) had an uneventful recovery without any complications. 21 patients (46 %) developed some form of complications but recovered successfully. Mortality was seen in only one patient in the conservatively treated group. In a resource poor setting such as Nepal, definitive management is not always possible. Conservative management of Acute Biliary Pancreatitis has a favorable outcome in the majority of our patients with acceptable morbidity and mortality. Definitive management can be safely performed during index admission where possible.

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Incidence, management and recurrence rate of acute pancreatitis

Cited by 108 publications

References 29 publications

The Risk Factors of Intensive Care Unit Admittance during First Attack of Acute Pancreatitis

The Risk Factors of Intensive Care Unit Admittance during First Attack of Acute Pancreatitis

Immediate oral feeding in patients with mild acute pancreatitis is safe and may accelerate recovery—A randomized clinical study

Acute Biliary Pancreatitis: An Experience in a Tertiary Level Hospital of Nepal

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