Increased chemerin serum levels in hyperandrogenic and normoandrogenic women from Argentina with polycystic ovary syndrome

Serum and follicular fluid chemerin and chemerin mRNA expression in women with polycystic ovary syndrome: Systematic review and meta‐analysis

“…However, based on the previous findings, 10,17,18,33,39,47,50,51 some factors or metabolic status such as type 2 diabetes mellitus, impaired glucose tolerance, metabolic syndrome, PCOS, BMI, fat mass or adipose tissue, fasting insulin, and IR, serum triglycerides, and blood pressure may influence serum and FF chemerin levels or ovarian chemerin mRNA expression, the data were weak or low for other variables (subcutaneous and omental adipose tissue chemerin mRNA expression or protein expression). It was notable that all studies showed serum or FF chemerin levels are higher in women with PCOS compared to the controls with regardless of another metabolic or androgenic status (BMI, insulin, IR and lipid profiles) 14,18,33,35,39,47 . The difference in the metabolic status may play a greater role in increased chemerin levels.…”

“…From 31 of the selected studies for full‐text screening, 22 studies met inclusion criteria after reading the full text. GetData Graph Digitizer software was used for the data extraction of some studies 10,17,18,32‐35 . Some data were received by email 35,36 .…”

“…In total, serum and FF chemerin levels were measured in nineteen 16‐18,32,33,35‐48 and four studies, 10,18,34,49 respectively. The methods of assessing serum and FF chemerin levels were ELISA 10,16‐18,32‐48 or Wb 49 .…”

“…In total, serum and FF chemerin levels were measured in nineteen 16‐18,32,33,35‐48 and four studies, 10,18,34,49 respectively. The methods of assessing serum and FF chemerin levels were ELISA 10,16‐18,32‐48 or Wb 49 . However, in total, five studies assessed chemerin mRNA expression in the subcutaneous and omental adipose tissues 17,32 and ovarian (granulosa cells in follicular fluid) 10,18,34 using reverse transcription‐polymerase chain reaction (RT‐PCR), due to the lack of data, only ovarian chemerin mRNA expression was analysed.…”

“…GetData Graph Digitizer software was used for the data extraction of some studies. 10 , 17 , 18 , 32 , 33 , 34 , 35 Some data were received by email. 35 , 36 The reasons for the exclusion of nine articles after reading full text were illustrated in Table S3 .…”