Increased dioxin-like compounds in the serum of women with peritoneal endometriosis and deep endometriotic (adenomyotic) nodules

Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data

“…Dioxin and other organochlorine chemicals have been shown to interfere with male and female reproductive development in experimental and wild animals, particularly during gestational exposure (Gao et al, 1999;Grey and Ostby, 1995;Roman et al, 1998;Sonne et al, 2006;Theobald et al, 1997). In studies of women with environmental or accidental exposures, associations between dioxin-like chemical exposures and various reproductive endpoints (Eskenazi et al, 2003;Lawson et al, 2004;Schnorr et al, 2001;Warner et al, 2004 and and endometriosis (Eskenazi et al, 2002;Fierens et al, 2003;Heilier et al, 2005;Hoffman et al, 2007) have been either absent or of unknown significance, though animal studies have demonstrated reproductive effects at high doses (Arisawa et al, 2005;U.S. EPA, 2004).…”

The Distribution of the MusselMytilusSpecies Along the Norwegian Coast

“…Animals at particular risk are fish-eating top predators, such as otters (Murk et al, 1998), seals (Vos et al, 2000) and birds (Bosveld, 1995;Henshel, 1998). The effects of dioxin-like compounds in humans include high acute toxicity, skin lesions, developmental and reproductive abnormalities, and probably cancer (WHO, 2000;Aylward et al, 2003;Heilier et al, 2005). It has been shown that aquatic organisms can ingest dioxin-like compounds that have been flushed into surface water from land, providing a potential pathway into the food chain (Leonards et al, 2008).…”

Endometriosis Among Women Exposed to Polybrominated Biphenyls

“…Several studies have found a positive association between endometriosis and dioxin or PCB exposure (13)(14)(15)(16)(17)(18), although some of the effects reported are imprecise. One study did not find an association between PCB exposure and endometriosis (19).…”