2019
DOI: 10.3382/ps/pez056
|View full text |Cite
|
Sign up to set email alerts
|

Increased fat synthesis and limited apolipoprotein B cause lipid accumulation in the liver of broiler chickens exposed to chronic heat stress

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

5
66
1
1

Year Published

2019
2019
2024
2024

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 90 publications
(73 citation statements)
references
References 42 publications
5
66
1
1
Order By: Relevance
“…Our previous study has shown that LXRα pathway is an important pathway changed by chronic heat stress to regulate fat synthesis in the liver of broilers . Previous studies suggested that the mRNA expression level of LXRα can be enhanced under stress conditions, which can activate the mRNA expression of SREBP‐1c in the liver .…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…Our previous study has shown that LXRα pathway is an important pathway changed by chronic heat stress to regulate fat synthesis in the liver of broilers . Previous studies suggested that the mRNA expression level of LXRα can be enhanced under stress conditions, which can activate the mRNA expression of SREBP‐1c in the liver .…”
Section: Discussionmentioning
confidence: 99%
“…In birds, most fat is synthesized by the liver, and the liver X receptor α (LXRα) acts as the regulator of fat synthesis and governs the expression of lipogenic enzymes and transcription factors . Our previous study has demonstrated that chronic heat stress enhanced the fat synthesis in the liver of broilers by activating the LXRα pathway . In addition, the triglycerides (TG) synthesized by the liver need to transport to extrahepatic tissues by the very‐low‐density lipoprotein (VLDL), otherwise the excessive lipids will accumulate in the liver, even resulting in hepatic steatosis …”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Generally, if nutrient intake is sufficient, the utilization rate of fat in the body increases, and the oxidation of non-esterified fatty acids (NEFAs) also increases. However, despite the decrease in livestock feed intake, such as in chickens and pigs, in a high-temperature environment, lipid accumulation in carcasses increases [ 27 , 28 ], implying that HS or high temperatures can reduce fat breakdown and increase fat storage metabolism in animals [ 27 ]. Although the energy demand for maintaining homeostasis increases during HS, adipose tissue contribution to energy production decreases [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
“…It is known that heat stress changes the biochemical blood parameters in poultry (13,20,34,38). Increased serum triglyceride (TG) levels indicate the changes in fat metabolism during heat stress in quails and broilers (11,20,38).…”
Section: Discussionmentioning
confidence: 99%