Increased Mortality Rate Associated with Chikungunya Epidemic, Ahmedabad, India

Abstract

A total of 3,056 excess deaths epidemiologically linked to chikungunya occurred in 2006.

Active Infection of Human Blood Monocytes by Chikungunya Virus Triggers an Innate Immune Response

“…During the last 8 y, major outbreaks have occurred among islands in the Indian Ocean (3), with Reunion Island being one of the most severely hit, with one-third of its population infected, and .240 deaths (8). During the same period in 2006, the virus also entrenched itself in India and caused an outbreak of unprecedented magnitude, affecting .1.39 million people (9), with a total of 2944 deaths reported during the epidemic (10). Outbreaks then spread to several countries in Southeast Asia, including Singapore (11,12).…”

Knowledge and Awareness Regarding Chikungunya among Urban Community People of Selected Area of Dhaka City Bangladesh

“…Since then Chikungunya has been reported in Burma, Thailand, Cambodia, Vietnam, India, Sri Lanka, Indonesia, West Africa and the Philippines [10]. In India, first outbreak occurred in Kolkata in 1963, since then a number of other outbreaks in Maharashtra, Andhra [10]. In 2010, the National Capital Region of India was the seroprevalence rate 9.91% [11].…”

“…In Asia Chikungunya virus was introduced subsequently where it has been transmitted from human to human mainly by Aedes aegypti and, to a lesser extent by Aedes albopictus through an urban and semi-urban transmission cycle [9]. Since then Chikungunya has been reported in Burma, Thailand, Cambodia, Vietnam, India, Sri Lanka, Indonesia, West Africa and the Philippines [10]. In India, first outbreak occurred in Kolkata in 1963, since then a number of other outbreaks in Maharashtra, Andhra [10].…”

Vitamin D deficiency may exacerbate or prolong arthritis in Chikungunya fever

“…9 Neither use of mechanical ventilation or fatality was reported in our study in contrast to increased death rates in previous reports. 10 Among laboratory reports 12% patients had a lower PCV in spite of normal hemoglobin. Elevated C-reactive protein was a consistent lab abnormality that was found in 86% of the patients (Figure 2).…”