Increased Oxidative Stress In Allergic Rhinitis. Attention; Ruywayda Adams

Abstract

There is a sample evidence that allergic disorders such as asthma, rhinitis and atopic dermatitis are mediated by oxidative stress. Excessive exposure to reactive oxygen and nitrogen species is the hallmark of oxidative stress and leads to damage of proteins, lipids and DNA. Oxidative stress occurs not only as a result of inflammation but also from environmental exposure to air pollution and cigarette smoke. The specific localization of antioxidant enzymes in the lung and the rapid reaction of nitric oxide with reactive oxygen species, such as superoxide, suggests that antioxidant enzymes might also function as cell-signalling agents or regulators of cell signalling.