Abstract:This is the first case report of acute sarcoidosis with increased serum thymidine kinase (TK) activity. A 43-yearold male presented fever, swelling of parotid glands, lymphadenopathy, and peripheral neuropathy. Sarcoidosis was pathologically diagnosed by lung and parotid gland biopsy.His serum TK, which was increased to ll.2 U// at diagnosis (normal <5U//), normalized after glucocorticoid therapy. Serum TK has been considered as a good marker of the proliferative activity of various types of neoplasms. Its ris… Show more
Although the data need to be validated by further investigation, the observations made in this study seem to indicate that serum chitotriosidase concentrations may be a useful marker for monitoring sarcoidosis disease activity and prognosis.
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