2012
DOI: 10.1182/blood.v120.21.4976.4976
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Increased Serum Transforming Growth Factor-beta1 (Tgf-beta1) Is Related to a Better Outcome in MM, WM and CLL Patients

Abstract: 4976 Background and Aims: TGF-beta1 normally down-regulates B-cell proliferation. Resistance to its effects is reported in malignant cells of B-lineage such as chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) cells. There are however very few studies on serum TGF-beta1 levels in patients with B-cell lymphoproliferative diseases and their eventual correlations with parameters of disease activity and survival. The purpose of our study was to assess … Show more

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“…Explanatory variables: age, 46–48,60,61,6371,74,77,80 serum LDH level, 46,51,62,64,65,73,76,7981,88 light chains level, 44,4654 β 2 microglobulin level, 51,62,64,70,71,7981,89,90 albumin level, 53,6466,71,79,80 M protein level, 59,70,9193 t(14), 55–59 pain, 69,83,85,…”
Section: Resultsmentioning
confidence: 99%
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“…Explanatory variables: age, 46–48,60,61,6371,74,77,80 serum LDH level, 46,51,62,64,65,73,76,7981,88 light chains level, 44,4654 β 2 microglobulin level, 51,62,64,70,71,7981,89,90 albumin level, 53,6466,71,79,80 M protein level, 59,70,9193 t(14), 55–59 pain, 69,83,85,…”
Section: Resultsmentioning
confidence: 99%
“…Dependent variables: OS, 4547,4951,5461,6365,67,68,7174,76,7881,8790,96122 β 2 microglobulin, 55,73,106,109,123126 serum LDH level, 62,88,112,117,120…”
Section: Resultsmentioning
confidence: 99%
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