Increased TGF-β1 level after cocoa administration during orthodontics tooth movement in Cavia cobaya
Annisa Nurul Fikri,
Cendrawasih Andusyana Farmasyanti,
Pinandi Sri Pudyani
Abstract:Background: Orthodontic tooth movement (OTM) is a process of tooth movement in the alveolar socket through a bone remodeling process. Cocoa contains caffeine as a bioactive component. The number of studies on the effects of caffeine on orthodontic tooth movement is rising. Purpose: This study aimed to determine the effect of caffeine in cocoa administration on TGF-β1 levels in the pressure side during orthodontic tooth movement. Methods: Twelve Cavia cobaya were divided into 4 groups: control group (ONC), trea… Show more
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