Incretin-Based Therapies: What Do We Need To Know?

Shehata, Marlene; Ph, Renton; Pharm, B.; Clinical,

doi:10.4172/2155-6156.1000146

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…The increasing prevalence of Type 2 diabetes is mainly due to reduced physical activity and consumption of unhealthy food and larger portion sizes in genetic susceptible individuals [16]. It is essential to note that the progressive nature of type 2 diabetes requires the combination of life style modification (diet and exercise) and antihyperglycemic agents in order to achieve adequate glycemic control [17].…”

Section: Type 2 Diabetesmentioning

confidence: 99%

Late Stage Complications of Diabetes and Insulin Resistance

Soumya¹,

Srilatha²

2011

J Diabetes Metab

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Diabetes mellitus is considered one of the main threats to human health in the 21st century. Diabetes is a metabolic disorder or a chronic condition where the sugar levels in blood are high. Diabetes is associated with long-term complications that affect almost every part of the body and often leads to blindness, heart and blood vessel disease, stroke, kidney failure, amputations, and nerve damage. Also it is associated with significantly accelerated rates of several debilitating microvascular complications such as nephropathy, retinopathy, and neuropathy, and macrovascular complications such as atherosclerosis and stroke. In the present article it has been discussed about the resistance of insulin and its consequences in diabetic patients. Insulin resistance results in various disorders. Metabolic syndrome is predicted to become a major public health problem in many developed, as well as developing countries. J ou rna l o f D ia be tes & M e ta bolism

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Section: Type 2 Diabetesmentioning

confidence: 99%

Late Stage Complications of Diabetes and Insulin Resistance

Soumya¹,

Srilatha²

2011

J Diabetes Metab

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“…The HNF4-α is a gene which codes for the transcription factor which regulates the gene transcription and expression in pancreatic beta cells. Which leads to Maturity-Onset Diabetes of the Young (MODY), an uncommon and autosomal dominant, non-insulin dependent form of diabetes [84]. This provides us information for a start for further study to make the easier way of Prognosis, Diagnosis and treatment.…”

Section: Molecular and Signaling Biomarkersmentioning

confidence: 99%

Biomarkers of Internal Origin and Their Significance in Diabetes and Diabetic Complications

YRKM¹,

Dattatreya²

2011

J Diabetes Metab

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This review is an overview on the modern diagnostic and prognostic biomarkers' for Diabetes and Diabetic complications. Here in this article we took various modernized and modern biomarkers' at a glance and had some hypothesis on the implications and also their pertinence of use in other appliances for the peculiar results of Interpretations. The prominent functions of certain biomarkers may give a conclusion that the dysfunction ability of it may give rise to severe and serious molestations. This indeed concludes in very sarcastic way that the marker itself is a reliever of the problem. Some does not intend themselves to be markers' but they'll be markers' in the diagnostic methods. This review prevails and perturbs the omnifarious biomarkers' in Diabetic complications. Journal of Diabetes and Metabolism J ou rna l o f D ia be tes & M e ta bolism

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Complications in Diabetes : A Review

Wagh¹,

Wagh

Upadhyay

et al. 2022

IJAR

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Diabetes is a disease chronic disease which affects global population from long time. This review is an update on unknown complications, causes, treatment modalities of this disease. This article also provides a summary on disease management through various strategies. Diabetic complications are the challenges associated with diabetes in the form of micro and macro vascular complications; microvascular compications include retinopathy, nephropathy and neuropathy whereas macrovascular compications include coronary artery disease (CAD), peripheral vascular disease (PVD) and cerebrovascular events (CVA). Complications of diabetes range from acute, life-threatening conditions such as severe hypoglycemia or ketoacidosis to chronic, debilitating complications affecting multiple organ systems, such as retinopathy, nephropathy, neuropathy, and cardiovascular disease. Estimates of the prevalence of diabetic complications are challenging, in part because there are no internationally agreed upon standards for diagnosis. This review is an update on unknown complications, causes, prevention and treatment of this disease. This article also provides a summary on disease management through various strategies.

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Incretin-Based Therapies: What Do We Need To Know?

Cited by 3 publications

References 5 publications

Late Stage Complications of Diabetes and Insulin Resistance

Late Stage Complications of Diabetes and Insulin Resistance

Biomarkers of Internal Origin and Their Significance in Diabetes and Diabetic Complications

Complications in Diabetes : A Review

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