“…ICA has been widely and successfully utilized in signal processing [6,7], image feature extraction [8,9], medical imaging [10,11], genomics and protein profiling [12,13], process monitoring [14,15]. ICA can separate the source signals with non-Gaussianity and statistically independent data, thus it has also successfully been applied in the areas of proteomics [13,16,17], transcriptome [18] and metabolomics [19][20][21][22][23][24].…”