Index finger and ring finger ratio (2D:4D) and it\'s correlation with Hypertension and it\'s affects for possibility factors in cardiovascular diseases in North Indian female population

Abstract

Hypertension is a major risk factor for cardiovascular diseases (CVDs) and is a growing concern globally. The 2nd to 4th digit ratio (2D:4D), determined by the relative length of the index and ring fingers, has been linked to prenatal testosterone exposure and potentially cardiovascular health. This study investigates the correlation between 2D:4D ratio and hypertension in a North Indian female population, exploring its potential role as a risk factor for CVDs. A cross-sectional study will be conducted among North Indian females. Participants will be recruited through community outreach and healthcare facilities. Data collection will involve: 1. Demographic information; 2. Blood pressure measurement to identify hypertensive and normotensive individuals; 3. Measurement of the 2nd and 4th finger lengths on both hands to calculate the 2D:4D ratio. The study is expected to reveal a correlation between 2D:4D ratio and hypertension prevalence in the North Indian female population. We hypothesize that females with a lower 2D:4D ratio (indicating higher prenatal testosterone exposure) might exhibit a higher prevalence of hypertension. This finding could suggest a potential association between prenatal hormonal influences and increased risk of CVDs in later life. This study design is cross-sectional, and causality cannot be established. Further longitudinal studies would be needed to explore the cause-and-effect relationship between 2D:4D ratio, hypertension, and CVD development.