Indigenous knowledge based herbal medicine for Corona treatment

Qaiser, M.; Nasar, Muhammad; Ali, Amjad

doi:10.30848/pjb2020-4(13)

Cited by 14 publications

(13 citation statements)

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“…A creative evaluation system should be developed before its use to prevent or treat COVID-19 [ 86 ]. Some researchers have suggested natural products obtained from plants might be an alternative option to treat COVID-19 [ 87 , 88 ].…”

Section: Discussionmentioning

confidence: 99%

The use of medicinal plants to prevent COVID-19 in Nepal

Khadka

Dhamala

et al. 2021

J Ethnobiology Ethnomedicine

101

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Background Medicinal plants are the fundamental unit of traditional medicine system in Nepal. Nepalese people are rich in traditional medicine especially in folk medicine (ethnomedicine), and this system is gaining much attention after 1995. The use of medicinal plants has increased during the COVID-19 pandemic as a private behavior (not under the control of government). A lot of misinterpretations of the use of medicinal plants to treat or prevent COVID-19 have been spreading throughout Nepal which need to be managed proactively. In this context, a research was needed to document medicinal plants used, their priority of use in society, their cultivation status, and the source of information people follow to use them. This study aimed to document the present status of medicinal plant use and make important suggestion to the concerned authorities. Methods This study used a web-based survey to collect primary data related to medicinal plants used during COVID-19. A total of 774 respondents took part in the survey. The study calculated the relative frequencies of citation (RFC) for the recorded medicinal plants. The relationship between plants recorded and different covariates (age, gender education, occupation, living place, and treatment methods) was assessed using Kruskal-Wallis test and Wilcoxon test. The relationship between the information sources people follow and the respondent characteristics was assessed using chi-square test. Results The study found that the use of medicinal plants has increased during COVID-19 and most of the respondents recommended medicinal plants to prevent COVID-19. This study recorded a total of 60 plants belonging to 36 families. The leaves of the plants were the most frequently used. The Zingiber officinale was the most cited species with the frequency of citation 0.398. Most of the people (45.61%) were getting medicinal plants from their home garden. The medicinal plants recorded were significantly associated with the education level, location of home, primary treatment mode, gender, and age class. The information source of plants was significantly associated with the education, gender, method of treatment, occupation, living with family, and location of home during the lockdown caused by COVID-19. Conclusions People were using more medicinal plants during COVID-19 claiming that they can prevent or cure COVID-19. This should be taken seriously by concerned authorities. The authorities should test the validity of these medicinal plants and control the flow of false information spread through research and awareness programs.

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Section: Discussionmentioning

confidence: 99%

The use of medicinal plants to prevent COVID-19 in Nepal

Khadka

Dhamala

et al. 2021

J Ethnobiology Ethnomedicine

101

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“…A creative evaluation system should be developed before its used to prevent or treat COVID-19 [81]. Some researchers have suggested natural products obtained from plants might be an alternative option to treat COVID-19 [82,83].…”

Section: Medicinal Plants Recorded and Frequency Of Citationmentioning

confidence: 99%

The Use of Medicinal Plant to Prevent COVID-19 in Nepal

Khadka

Dhamala

et al. 2020

Preprint

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Background: Medicinal plants are the fundamental unit of traditional medicine system in Nepal. Nepalese people are rich in traditional medicine especially in folk medicine (ethnomedicine) and this system is gaining much attention after 1995. The use of medicinal plants have increased during COVID-19 pandemic as a private behavior (not under the control of government). Lot of misinterpretations of the use of medicinal plants to treat or prevent COVID-19 have been spreading throughout Nepal which need to be managed proactively. In this context, a research was needed to document medicinal plants used, their priority of use in society, cultivation status and source of information people follow to use them. This study aimed to document the present status of medicinal plant use and make important suggestion to the concern authorities.Methods: This study used a web-based survey to collect primary data related to medicinal plants used during COVID-19. A total of 774 respondents took part in the survey. The study calculated the relative frequencies of citation (RFC) for the recorded medicinal plants. The relationship between plants recorded and different covariates (age, gender education, occupation, living place, and treatment methods were assessed using Kruskal Wallis test and Wilcox test. The relationship between the information sources people follow and respondent characteristics, were assessed using chi-square test.Results:The study found that the use of medicinal plants has increased during COVID-19 and most of the respondents recommended medicinal plants to prevent COVID-19. This study recorded a total of 63 plants belonging to 42 families. The leaves of the plants were the most frequently used. The Zingiber officinale was the most cited species with the frequency of citation 0.398. Most of the people (45.61%), were getting medicinal plants from their home garden. The medicinal plants recorded were significantly associated with the education level, location of home, primary treatment mode, gender, and age class. The information source of plants was significantly associated with the education, gender, method of treatment, occupation, living with family, and location of home during lockdown caused by COVID-19.Conclusions:People were using more medicinal plants during COVID-19 claiming that they can prevent or cure COVID-19. This should be taken seriously by concerned authorities. The authorities should test the validity of these medicinal plants and control the flow of false information spread through research and awareness programs.

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“…[29,30] Moreover, studies with phytochemicals derived from natural sources showed that bioactive compounds have already been effective against coronaviruses [31] by increasing the immunity system or destroying the pathogens, which has received attention as an alternative source of drugs with fewer side effects. [32][33][34] In this context, nanoflora-nanoparticles improving bioactive compounds′ bioavailability-was reported to enhance the delivery of insoluble phytochemicals repurposing antimicrobial drugs, [35][36][37] including therapeutics approaches against viruses [38][39][40] and and coronaviruses (CoVs). [41,42] However, only after the COVID-19 emergence, a considerable number of papers has been published on nanomaterialsbased platforms and coronaviruses, although the first studies initiate after the first coronavirus pandemic, the 2002-2004 severe acute respiratory syndrome (SARS)-Figure 1 shows the number of publications retrieved in a simple search in some databases related to the topics "nano" and "coronavirus" between January 1, 2004 and December 31, 2020.…”

mentioning

confidence: 99%

Recent Advances on Nanomaterials to COVID‐19 Management: A Systematic Review on Antiviral/Virucidal Agents and Mechanisms of SARS‐CoV‐2 Inhibition/Inactivation

Carvalho

Conté-Júnior

2021

Global Challenges

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A novel beta-coronavirus, the novel coronavirus (SARS-CoV-2), or the severe acute respiratory syndrome coronavirus 2, was described as the causative agent of the pneumonia outbreak of coronavirus disease 2019 (COVID-19), first reported in December 2019 in a local seafood market of Wuhan, Hubei province, China. [1,2] The same beta-coronavirus genus of SARS-CoV-2 was earlier the causative of viral pneumonia pandemics caused by severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) that emerged in 2002 in China and 2012 in the Arabian Peninsula, respectively. [3] The World Health Organization reported, globally, as of 30 January 2021, more than 101 million confirmed cases of COVID-19 and 2 196 944 deaths. [4] Due to lockdown and quarantine, humanity is now facing its worst economic crisis since World WarThe current pandemic of coronavirus disease 2019 (COVID-19) is recognized as a public health emergency of worldwide concern. Nanomaterials can be effectively used to detect, capture/inactivate or inhibit coronavirus cell entry/ replication in the human host cell, preventing infection. Their potential for nanovaccines, immunoengineering, diagnosis, repurposing medication, and disinfectant surfaces targeting the novel coronavirus (SARS-CoV-2) is highlighted. In this systematic review the aim is to present an unbiased view of which and how nanomaterials can reduce the spread of COVID-19. Herein, the focus is on SARS-CoV-2, analyzing 46 articles retrieved before December 31, 2020. The interface between nanomaterials is described, and the main mechanisms to inhibit SARS-CoV-2 pathogenesis and viral inactivation are also discussed. Nanocarbons, biopolymeric, copper, and silver nanoparticles are potential antiviral and virucidal agents toward self-cleaning and reusable filter media and surfaces (e.g., facial masks), drug administration, vaccines, and immunodiagnostic assays. Trends in toxicology research and safety tests can help fill the main gaps in the literature and overcome health surveillance's challenges. Phytochemicals delivery by nanocarriers also stand out as candidates to target and bio-friendly therapy. Nanocellulose might fill in the gaps. Future research using nanomaterials targeting novel therapies/prophylaxis measures to COVID-19 and future outbreaks is discussed.

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Indigenous knowledge based herbal medicine for Corona treatment

Cited by 14 publications

References 0 publications

The use of medicinal plants to prevent COVID-19 in Nepal

The use of medicinal plants to prevent COVID-19 in Nepal

The Use of Medicinal Plant to Prevent COVID-19 in Nepal

Recent Advances on Nanomaterials to COVID‐19 Management: A Systematic Review on Antiviral/Virucidal Agents and Mechanisms of SARS‐CoV‐2 Inhibition/Inactivation

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