Individualized pharmaceutical care for a patient after pancreaticoduodenectomy with trypsin replacement nutritional therapy: A case report

Abstract

Rationale: Optimal nutritional therapy for pancreaticoduodenectomy (PD) has been debated; however, little is known about key points of pancreatin enteric-coated capsule administration, a critical component of the PD treatment regimen. Patients often report elevations in tablet platoon and steatorrhea, and steatorrhea may adversely affect nutritional therapy for PD. Herein, we report a case of individualized pharmaceutical care for a patient after PD with trypsin replacement nutritional therapy. Patient concerns and diagnosis: After PD with trypsin replacement nutritional therapy, the patient developed acute steatorrhea. Intervention: Individualized pharmaceutical care was provided by clinical pharmacists to address intolerance to pancreatin enteric-coated capsules following PD. Outcomes: The clinical pharmacist’s integration into the patient’s treatment plan enhanced pharmacotherapy optimization, especially through pharmacokinetic monitoring and interventions related to nutritional therapy. Lesson: Pharmaceutical care by clinical pharmacists aids in ensuring the safety and efficacy of drugs and nutritional treatment. Clinical pharmacists should be members of the nutrition support team.

Impacto da atuação do farmacêutico no âmbito hospitalar: uma revisão integrativa

“…Dessa forma conseguiu-se potencializar a farmacoterapia, sobretudo através do controle farmacocinético e das intervenções referentes à terapia nutricional. (Zhang et al, 2022);…”