Indocyanine based dual optical probe for cyanide in HEPES buffer

Kim, Chae Yeong; Park, Seokan; Kim, Hae-Jo

doi:10.1016/j.dyepig.2016.03.030

Cited by 19 publications

(3 citation statements)

References 33 publications

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“…The intensity increase almost terminates within 3 min, indicating that only 3 min assay is required for CN – sensing. This assay time can be classified as one of the shortest class among the early reported CN – receptors. − In the case for CN – detection by the receptor 1 , preliminary UV irradiation (ca. 30 min) is necessary to produce the MC form (Scheme ).…”

Section: Resultsmentioning

confidence: 99%

“…A number of receptors that detect very small amounts of CN – (<1.9 μM) at reliable levels [signal-to-background (S/B) ratio ≥ 3] have been proposed. Some of these receptors, however, produce metal salts or halogens as waste. − Other receptors act only in organic media, − show insufficient selectivity, − or need a long time (>30 min) for detection. − To the best of our knowledge, there is no report of a receptor that overcomes all of these issues. The design of a new receptor that facilitates rapid, selective, and sensitive detection of CN – is therefore necessary.…”

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confidence: 99%

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Coumarin–Spiropyran Dyad with a Hydrogenated Pyran Moiety for Rapid, Selective, and Sensitive Fluorometric Detection of Cyanide Anion

et al. 2016

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We synthesized a coumarin-spiropyran dyad with a hydrogenated pyran moiety (2), behaving as an off-on type fluorescent receptor for rapid, selective, and sensitive detection of cyanide anion (CN(-)) in aqueous media. The receptor itself shows almost no fluorescence with a quantum yield < 0.01, due to the delocalization of π-electrons over the molecule. Selective nucleophilic addition of CN(-) to the spirocarbon of the molecule rapidly promotes spirocycle opening within only 3 min. This leads to localization of π-electrons on the coumarin moiety and exhibits strong light-blue fluorescence at 459 nm with very high quantum yield (0.52). As a result of this, the receptor facilitates rapid, selective, and sensitive fluorometric detection of CN(-) as low as 1.0 μM.

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Section: Resultsmentioning

confidence: 99%

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confidence: 99%

Coumarin–Spiropyran Dyad with a Hydrogenated Pyran Moiety for Rapid, Selective, and Sensitive Fluorometric Detection of Cyanide Anion

et al. 2016

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“…The reaction was carried out according to the modified literature procedure . To a colorless solution of N -hydroxyethyltrimethylindolium bromide (283 mg, 1.00 mmol) and 4-hydroxybenzaldehyde (146 mg, 1.20 mmol) in EtOH (2 mL) was added Et 3 N (2 drops).…”

Section: Methodsmentioning

confidence: 99%

Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine

et al. 2016

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We report a chromogenic and fluorescence turn-on probe based on crotonoyl ester-functionalized oxazolidinoindole for the selective detection of cysteine in neutral buffer. The probe rapidly formed indocyanophenolate through the Michael addition and a subsequent cyclization reaction of cysteine, inducing both a dramatic bathochromic shift (>130 nm) and a large fluorescence turn-on response (F/F0 12) in the UV-vis and fluorescence spectra and affording a micromolar limit of detection (LOD = 5.0 μM) of cysteine in HEPES buffer. When cysteine was added, the probe exhibited a dual optical change with strong green fluorescence and dramatic red color by the oxazolidinoindole-to-hydroxyethylindolium transformation. Further cellular application of the probe was successfully performed for the mitochondrial imaging of HeLa cells.

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Colorimetric Chemosensors for the Detection of Environment‐Polluting Arsenite and Cyanide

Nagaraj,

Shetty,

Trivedi

2023

Organic and Inorganic Materials Based Sensors

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Indocyanine based dual optical probe for cyanide in HEPES buffer

Cited by 19 publications

References 33 publications

Coumarin–Spiropyran Dyad with a Hydrogenated Pyran Moiety for Rapid, Selective, and Sensitive Fluorometric Detection of Cyanide Anion

Coumarin–Spiropyran Dyad with a Hydrogenated Pyran Moiety for Rapid, Selective, and Sensitive Fluorometric Detection of Cyanide Anion

Mitochondria-Targeting Chromogenic and Fluorescence Turn-On Probe for the Selective Detection of Cysteine by Caged Oxazolidinoindocyanine

Colorimetric Chemosensors for the Detection of Environment‐Polluting Arsenite and Cyanide

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