Indomethacin in the Treatment of Ureteral Colic: Is Fluid Restriction Necessary?

Edna, Tom-Harald; Hesselberg, Fredrik; Loe, B

doi:10.1016/s0022-5347(17)44877-4

Cited by 5 publications

(1 citation statement)

References 16 publications

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“…Fluid restriction was also prescribed in one-third of cases, despite the lack of validated eect on AARC [23,24]. Pain management in EDs remains a current practice problem, underlining the need to improve pain assessment in this context [25,26].…”

Section: Discussionmentioning

confidence: 99%

Treatment of acute renal colic in a French emergency department: a comparison of simulated cases and real cases in acute pain assessment and management

Jean

et al. 2001

Eur J Clin Pharmacol

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Section: Discussionmentioning

confidence: 99%

Treatment of acute renal colic in a French emergency department: a comparison of simulated cases and real cases in acute pain assessment and management

Jean

et al. 2001

Eur J Clin Pharmacol

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Oral indomethacin for acute renal colic

Wolfson¹,

Yealy

1991

The American Journal of Emergency Medicine

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Indomethacin as Prophylaxis Against Ureteral Colic Following Extracorporeal Shock Wave Lithotripsy

et al. 1989

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Ureteral colic occurs in 24 to 34 per cent of all patients following extracorporeal shock wave lithotripsy. Recent research has shown prostaglandin synthetase inhibitors to be effective in relieving the pain associated with ureteral colic. Our prospective, controlled, double-blind, randomized study was designed to test the efficacy of indomethacin in the prophylactic treatment of pain after extracorporeal shock wave lithotripsy. Patients undergoing extracorporeal shock wave lithotripsy were randomized into 2 groups. Group 1 received 100 mg. indomethacin suppositories twice daily and group 2 received placebo suppositories. After extracorporeal shock wave lithotripsy 2 analgesics were available to the patients: oral co-dydramol or intramuscular pethidine was offered in the normal manner by the nursing staff. The pre-extracorporeal shock wave lithotripsy x-ray was used to make a quantitative estimate of the total stone burden in each patient. The post-extracorporeal shock wave lithotripsy analgesic requirement was used to compare the 2 groups. Of 112 patients recruited to the study 55 received indomethacin and 57 received placebo. The request for analgesia in the 2 groups was not different (28 of 55 and 33 of 57, respectively). However, in the indomethacin group only 6 patients required pethidine (10 doses), compared to 18 (41 doses) in the placebo group. This difference is statistically significant (p less than 0.01). There was no difference between the 2 groups in the occurrence of ureteral steinstrasse. Indomethacin has been shown to be effective in the prophylactic treatment of ureteral colic after lithotripsy.

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Indomethacin in the Treatment of Ureteral Colic: Is Fluid Restriction Necessary?

Cited by 5 publications

References 16 publications

Treatment of acute renal colic in a French emergency department: a comparison of simulated cases and real cases in acute pain assessment and management

Treatment of acute renal colic in a French emergency department: a comparison of simulated cases and real cases in acute pain assessment and management

Oral indomethacin for acute renal colic

Indomethacin as Prophylaxis Against Ureteral Colic Following Extracorporeal Shock Wave Lithotripsy

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