Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia

Jordan, Andreas; Wust, Peter; Fähling, H.; John, W.; Hinz, Andreas M.; Félix, R.

doi:10.3109/02656730903287790

Cited by 230 publications

(223 citation statements)

References 21 publications

Supporting

Mentioning

219

Contrasting

Unclassified

Order By: Relevance

“…The heating efficiency increases systematically with the increase of the amplitude of magnetic field. The specific loss power SLP was calculated using the formula [17,18]:…”

Section: Resultsmentioning

confidence: 99%

Phase Structure and Heat Generation in the Co-Precipitated Magnetite Nanoparticles

et al. 2017

View full text Add to dashboard Cite

In the present studies the phase structure and magnetic ordering of magnetite nanoparticles were investigated. The powder samples were obtained by co-precipitation from Fe(III) and Fe(II) salts. SiO2 coating was performed using the modified Stöber process. X-ray diffraction studies revealed presence of the only one Fe3O4 crystalline phase both for the non-coated and SiO2-coated samples. The Mössbauer studies have shown differences in shapes of measured spectral lines for Fe3O4 particles subjected to the Stöber process and non-coated particles. The heating efficiency was measured for glycerol dispersed nanoparticles. The analysis have shown changes in specific loss power depending on the concentration of the nanoparticles and amplitude of alternating magnetic field.

show abstract

“…The heating efficiency increases systematically with the increase of the amplitude of magnetic field. The specific loss power SLP was calculated using the formula [17,18]:…”

Section: Resultsmentioning

confidence: 99%

Phase Structure and Heat Generation in the Co-Precipitated Magnetite Nanoparticles

et al. 2017

View full text Add to dashboard Cite

show abstract

“…[705] It has been proven that magnetic particles in the range of nanometer have higher heating efficiencies compared to micrometric particles. [706] In addition to size, other effective parameters are shape, crystal structure, magnetic anisotropy of MNPs as well as amplitude and frequency of the applied alternative magnetic field. [707] Hysteresis is the main source of generating heat in large MNPs (>100 nm), which is caused by the coupling of atomic spins to the crystal lattice.…”

Section: Wwwadvancedsciencenewscom Wwwadvhealthmatdementioning

confidence: 99%

Synthesis, Functionalization, and Design of Magnetic Nanoparticles for Theranostic Applications

Mosayebi

Kiyasatfar

Laurent

2017

Adv Healthcare Materials

203

171

View full text Add to dashboard Cite

In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs) have been presented as a class of non‐invasive nanomaterials for numerous biomedical applications. In particular, MNPs have opened a door for simultaneous diagnosis and brisk treatment of diseases in the form of theranostic agents. This review highlights the recent advances in preparation and utilization of MNPs from the synthesis and functionalization steps to the final design consideration in evading the body immune system for therapeutic and diagnostic applications with addressing the most recent examples of the literature in each section. This study provides a conceptual framework of a wide range of synthetic routes classified mainly as wet chemistry, state‐of‐the‐art microfluidic reactors, and biogenic routes, along with the most popular coating materials to stabilize resultant MNPs. Additionally, key aspects of prolonging the half‐life of MNPs via overcoming the sequential biological barriers are covered through unraveling the biophysical interactions at the bio–nano interface and giving a set of criteria to efficiently modulate MNPs' physicochemical properties. Furthermore, concepts of passive and active targeting for successful cell internalization, by respectively exploiting the unique properties of cancers and novel targeting ligands are described in detail. Finally, this study extensively covers the recent developments in magnetic drug targeting and hyperthermia as therapeutic applications of MNPs. In addition, multi‐modal imaging via fusion of magnetic resonance imaging, and also innovative magnetic particle imaging with other imaging techniques for early diagnosis of diseases are extensively provided.

show abstract

“…Large ferro-or ferri-magnetic particles dissipate heat through hysteresis effects in the form of domain wall motion, also called hysteresis losses [25][26][27]. Superparamagnetic nanoparticles allow heating through Brownian or Né el magnetic relaxation [28][29][30][31][32]. As for the latter, the negligible dipole-dipole magnetic interactions with coated particles (the coatings prevent surface interactions) allow for the safe injection in human bodies without the risk of adverse aggregation [33].…”

Section: Introductionmentioning

confidence: 99%

Magnetic and in vitro heating properties of implants formed in situ from injectable formulations and containing superparamagnetic iron oxide nanoparticles (SPIONs) embedded in silica microparticles for magnetically induced local hyperthermia

Renard

Lortz

Senatore

et al. 2011

Journal of Magnetism and Magnetic Materials

View full text Add to dashboard Cite

a b s t r a c tThe biological and therapeutic responses to hyperthermia, when it is envisaged as an anti-tumor treatment modality, are complex and variable. Heat delivery plays a critical role and is counteracted by more or less efficient body cooling, which is largely mediated by blood flow. In the case of magnetically mediated modality, the delivery of the magnetic particles, most often superparamagnetic iron oxide nanoparticles (SPIONs), is also critically involved. We focus here on the magnetic characterization of two injectable formulations able to gel in situ and entrap silica microparticles embedding SPIONs. These formulations have previously shown suitable syringeability and intratumoral distribution in vivo. The first formulation is based on alginate, and the second on a poly(ethylene-co-vinyl alcohol) (EVAL). Here we investigated the magnetic properties and heating capacities in an alternating magnetic field (141 kHz, 12 mT) for implants with increasing concentrations of magnetic microparticles. We found that the magnetic properties of the magnetic microparticles were preserved using the formulation and in the wet implant at 37 1C, as in vivo. Using two orthogonal methods, a common SLP (20 W g À 1 ) was found after weighting by magnetic microparticle fraction, suggesting that both formulations are able to properly carry the magnetic microparticles in situ while preserving their magnetic properties and heating capacities.

show abstract

Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia

Cited by 230 publications

References 21 publications

Phase Structure and Heat Generation in the Co-Precipitated Magnetite Nanoparticles

Phase Structure and Heat Generation in the Co-Precipitated Magnetite Nanoparticles

Synthesis, Functionalization, and Design of Magnetic Nanoparticles for Theranostic Applications

Magnetic and in vitro heating properties of implants formed in situ from injectable formulations and containing superparamagnetic iron oxide nanoparticles (SPIONs) embedded in silica microparticles for magnetically induced local hyperthermia

Contact Info

Product

Resources

About