Inductively coupled plasma- and glow discharge plasma-sector field mass spectrometry : Part II. Applications

Abstract

Part I of this series of two reviews focused on fundamentals, instrumentation and operation of sector field instruments to give a proper overview of the capabilities of the actual commercially available instrumentation. In part II, selected applications of the last decade are discussed in detail concluding with pinpointing possible future trends and current developments.

Inductively Coupled Plasma Mass Spectrometry

“…Therefore, it is rather the aim of this section to demonstrate the versatility of the instrumentation and to highlight publications reporting scientific progress in various disciplines facilitated by data generated using MC ICP-MS instruments. We hope to spark the interest in the diverse applications of the method and refer the reader who wants to learn more to the bibliography given and in particular to several general reviews dealing exclusively with or including MC ICP-MS. 39,59,404,405 In general, MC ICP-MS can be used to monitor natural variation in the isotopic composition of practically all elements with Z2 isotopes, be it due to radioactive decay processes, mass-dependent or the more recently discovered mass-independent fractionation. Furthermore, artificially induced changes by use of an enriched tracer can also be investigated.…”

Determination of trace elements in high purity alumina powder by helium enhanced direct current glow discharge mass spectrometry

“…Glow discharge mass spectrometry (GD-MS) is one A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT 4 of the most powerful methods for rapid multi-elemental analysis of high purity materials at the trace and ultra-trace levels [18,19]. Its main advantages are minimum sample preparation [20], little matrix dependence due to the separated process between atomization and ionization in space and time [21], and the quantification of trace element concentrations [22].…”

The benefits and limitations of reaction cell and sector field inductively coupled plasma mass spectrometry in the detection and quantification of phosphopeptides

“…For the determination of phosphorus and sulfur, a resolution of 4000 is sufficient to completely resolve them from polyatomic interferences. Compared to quadrupole instruments, higher ion transmission and lower vacuum conditions enables higher sensitivity . However, this high‐resolution instrument has two major disadvantages: (1) the instrument is 2 to 3 times more expensive in comparison with a quadrupole‐based instrument and (2) it has a reduced signal intensity at medium/high resolution compared to low‐resolution measurements on the same instrument due to a reduction in transmission of the analyte.…”