Infants Born to Mothers Seropositive for Human Immunodeficiency Virus

Mok, J.; Rossi, Anita De; Ades, A E; Giaquinto, Carlo; Grosch-Wörner, I.; Peckham, Catherine

doi:10.1016/s0140-6736(87)92142-8

Cited by 190 publications

(27 citation statements)

References 27 publications

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“…The risk of infecting either one's partner or one's child is considerably greater at the later symptomatic stage of the disease. Mok et al (1987) report that AIDS/ARC was 9-4 times more likely in children followed up to a median age of 6 months whose mothers had symptoms before delivery than in those whose mothers had no symptoms. (Babies born to women with HIV all have maternal antibodies and therefore test HIV-antibody positive at birth.…”

Section: Introductionmentioning

confidence: 99%

The reproductive careers of a cohort of men and women following an HIV-positive diagnosis

Green¹

1994

J. Biosoc. Sci.

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This report examines the consequences of a positive HIV diagnosis upon the reproductive decision-making of 39 men and women in Scotland. Whilst the majority initially decide never to have any (more) children this sometimes changes as other factors gain ascendancy, such as a partner wanting 'their' child, and about one-third had had a child or were intending to do so. The motivations underlying such decisions are discussed and ways in which health services could intervene to support people with HIV in making reproductive choices and to minimise the risk of transmission to an HIV-negative partner and the child are suggested.

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Section: Introductionmentioning

confidence: 99%

The reproductive careers of a cohort of men and women following an HIV-positive diagnosis

Green¹

1994

J. Biosoc. Sci.

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“…However, not all pregnancies in HIV-infected women result in an infected baby. The rate of maternal/fetal transmission ranges from 25% to 65% (2)(3)(4). The identification of factors that influence this mode of transmission is critical.…”

mentioning

confidence: 99%

Vertical transmission of human immunodeficiency virus is correlated with the absence of high-affinity/avidity maternal antibodies to the gp120 principal neutralizing domain.

Devash

Calvelli

Wood

et al. 1990

Proc. Natl. Acad. Sci. U.S.A.

195

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“…These antibodies will usually disappear within 12 months and only a proportion will show evidence of continuing infection. In a study involving 3 European centres, 71 children of HIV seropositive mothers were followed up for periods of up to 15 months (Mok et al, 1987). Symptoms of AIDS or ARC developed in 5 during this time and another 4 had substantial symptoms which could have been indicative of HIV infection.…”

Section: Vertical Transmissionmentioning

confidence: 99%