Infection with hepatitis B virus after open heart surgery.

Prentice, Michael B.; Flower, A. J. E.; Morgan, Gaylon; Nicholson, Karl G.; Rana, Bardan J.; Firmin, Richard K.; Mitchell, Chris

doi:10.1136/bmj.304.6829.761

Cited by 39 publications

(16 citation statements)

References 19 publications

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“…One factor associated with increased risk of transmission is the HCW being HBeAg positive, indicating a higher level of infectivity (137,138,217,218,221,275). In the United Kingdom, several episodes of HBeAg-negative surgeons transmitting HBV have been reported (127,128,145,250).…”

Section: Transmission Of Hbv From Infected Hcws To Patientsmentioning

confidence: 99%

Risk and Management of Blood-Borne Infections in Health Care Workers

Beltrami¹,

Williams

Shapiro

et al. 2000

Clinical Microbiology Reviews

355

209

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Section: Transmission Of Hbv From Infected Hcws To Patientsmentioning

confidence: 99%

Risk and Management of Blood-Borne Infections in Health Care Workers

Beltrami¹,

Williams

Shapiro

et al. 2000

Clinical Microbiology Reviews

355

209

View full text Add to dashboard Cite

“…This had previously been associated with the transmission of hepatitis B virus. 57 In the UK there are two reports of transmission of HCV from surgeon to patient.…”

Section: Risk To Patientsmentioning

confidence: 99%

Hepatitis C Virus: An Important Occupational Hazard?

Stevens¹,

Coyle²

2000

Occupational Medicine

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Infection with Heptatis C virus (HCV) is estimated to affect 3% of the world's population and is an important cause of liver disease. It is most commonly transmitted by percutaneous exposure. Although current evidence does not suggest an increased prevalence of HCV infection among healthcare workers, transmission of infection following occupational exposure has been demonstrated. An average transmission rate of 1.8%, following percutaneous injury, has been reported. The risk of transmission is higher from patients with viraemia, as measured by a positive polymerase chain reaction for HCV RNA. After exposure to HCV, healthcare workers should be actively followed up, initially using a test to detect viral RNA. This may faciliate earlier diagnosis and treatment. Recent reports in the UK, of transmission of infection to patients from HCV infected healthcare workers, have prompted a review of the appropriateness of HCV infected individuals undertaking exposure prone procedures.

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“…Ein zweiter Allgemeinchirurg wies eine Übertragungsrate von 2,8% und eine DNA-Konzentration von 10 9 Molekülen/ml [26]. Unter den Ärzten mit einer besonders hohen Übertragungsrate fanden sich 5 Thoraxchirurgen [27,28,29,30] und 2 Gynäkologen [31,32]. In der Studie von Welch [32] wurde gezeigt, dass bei einer Gesamtübertragungsrate von 9% durch einen Gynäkologen Hysterektomie (24%) und Kaiserschnitt (20%) mit einer besonders hohen Rate belastet waren, während diese bei den anderen Eingriffen nur bei 1,4% lag.…”

Section: Hbeag-positive Hbv-trägerunclassified

Hepatitis B und C

Gerlich

2004

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschu

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Hepatitis B and C viruses (HBV, HCV) cause chronic infections and high viremia which often remain undetected. Health care workers have an elevated risk of acquiring HBV or HCV when performing exposure-prone procedures and transmitting these viruses to patients. The extent of viremia varies considerably in different carriers and the risk of transmission is different for the various procedures. According to reports from the last 15 years, highly viremic HBV carriers with HBeAg transmit the virus on average to 4% of their patients when performing operations with high risk of injuries. HBeAg-negative surgeons with a viremia between 10(6) and 10(7) HBV DNA molecules/ml transmit to 1.5% of the patients. The absence of reports on proven transmission caused by viremia <10(5) molecules/ml suggests a residual risk below 1:100,000 that a surgeon with lower virus load transmits to one patient within 15 years. Eight cases were reported where HCV-infected surgeons transmitted the virus to 0.15% of their patients (17/11,119) and had (as far as tested) around 10(6) HCV RNA molecules/ml or more. Current recommendations of the relevant professional associations and institutions require vaccination of medical staff against HBV with control of immunity, regular examinations of staff for HCV, and in cases of missing immunity for HBV. Infected staff with viremia must either abstain from exposure-prone procedures or have a decision from an expert committee on the acceptability of such procedures in view of the individual infection status.

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Infection with hepatitis B virus after open heart surgery.

Cited by 39 publications

References 19 publications

Risk and Management of Blood-Borne Infections in Health Care Workers

Risk and Management of Blood-Borne Infections in Health Care Workers

Hepatitis C Virus: An Important Occupational Hazard?

Hepatitis B und C

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