Infertility and mortality

Stentz, N.C.; Koelper, Nathanael; Barnhart, Kurt T.; Sammel, Mary D.; Senapati, Suneeta

doi:10.1016/j.ajog.2019.09.007

Cited by 39 publications

(22 citation statements)

References 45 publications

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“…Further, our results may highlight the findings from survival analyses of two large-scale studies, Stentz et al. ( 36 ) and Parikh et al. ( 37 ) who found no significant difference in the risk of death from CVDs between infertile and noninfertile women (mean age= 62.5 years) over 10 years and no association between history of infertility and CVDs in postmenopausal women (mean age= 63.2 years), respectively.…”

Section: Discussionsupporting

confidence: 77%

“…Most published studies have tested the association of infertility with CVDs and not with hs-CRP ( 12 , 35 , 36 , 37 ). Our results are consistent with the subgroup analysis of NHANES data by Gleason and colleagues ( 12 ), where they reported no increased odds of CVDs among self-reported infertile women who gave birth but not with their results of overall higher odds of CVDs (83%) among infertile women aged 20–59 years.…”

Section: Discussionmentioning

confidence: 99%

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High-sensitivity C-reactive protein is not independently associated with self-reported infertility in National Health and Nutrition Examination Survey 2015–2018 data

et al. 2022

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

High-sensitivity C-reactive protein is not independently associated with self-reported infertility in National Health and Nutrition Examination Survey 2015–2018 data

et al. 2022

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“…Infertility is a medical disorder or scientific concept for people who do not have the potential to achieve conception from unsafe sexual intercourse for a span of 12 months (Stentz et al 2019), there are two main forms of infertility (1) Primary infertility: It is infertility, in which no pregnancy happens indefinitely. (2) Secondary infertility: It is the form in which a condition of non-pregnancy occurs after a previous pregnancy or childbirth has occurred (Keskin et al 2011).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Copper Oxide and Selenium Nanoparticles on Vitamin D Levels in Women With Infertility

Al-Kazaz¹,

Hussain²,

Khalaf³

2021

PLANT ARCHIVES

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The nanoparticles of both copper oxide (CuO NPs) and selenium (Se NPs) were synthesized by a laser ablation method that is fast and safe in biological applications. It was Characterization by atomic force microscopy (AFM), Xray diffraction (XRD), field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM), which showed that the size of the nanoparticles was 20-23 nm for Se NPs and 19-23 nm for CuO NPs. The effectiveness of these nanoparticles was examined on vitamin D levels in the group of women with primary infertility (PP) and the group of women with secondary infertility (SP). The results showed a highly significant activation effect of the copper oxide nanoparticles, with an activation rate equal to 13% for the primary sterility group (P = 0.003) and 23% for the secondary sterility group (P = 0.00

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“…Given the nonspecific symptoms and aggressive natural history of EOC, and of most importance, the lack of established or effective screening test, the identification of risk factors, which have consistently been linked to EOC and additional risk-reductive strategies, are very important. [12][13][14][15][16][17][18][19][20][21][22][23][24] Many factors are reported to have a correlation with the development of EOC. For example, endometriosis has long been shown to be risky of the development of EOC.…”

Section: Introductionmentioning

confidence: 99%

<p>Subsequent Development of Epithelial Ovarian Cancer After Ovarian Surgery for Benign Ovarian Tumor: A Population-Based Cohort Study</p>

Huang¹,

Chang²,

Huang³

et al. 2020

CLEP

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The goal of the current study is to determine the risk of subsequent development of epithelial ovarian cancer (EOC) in women after ovarian surgery for benign ovarian tumors. Patients and Methods: We conducted the nationwide population-based historic cohort study using the National Health Insurance Research Database (NHIRD) of Taiwan. Eleven thousand six hundred twenty women who underwent ovarian surgery for ovarian benign diseases were analyzed. The collected data included age, types of ovarian surgery, medical history by Charlson comorbidity index (CCI), infertility (yes/no), pelvic inflammatory disease (PID) (yes/no), tubal ligation (yes/no), total/subtotal hysterectomy (TH/STH) (yes/no), and endometrioma (yes/no). We used the Kaplan-Meier method and the Log-rank test to evaluate the risk factors. Cox proportional hazard methods were used to evaluate risk factors for the subsequent development of EOC. Multivariate analysis using Cox stepwise forward regression was conducted for the covariate selected in univariate analysis. Hazard ratio (HR) and 95% confidence interval (CI) were calculated using the Wald test. Results: Subsequent EOC incidence rate (IR, incidence per 10,000 person-years) of women after ovarian surgery for benign ovarian tumors was 2.98. Separating into four groups based on different age, IR of EOC was 1.57 (<30 years), 4.71 (30-39 years), 3.59 (40-49 years) and 0.94 (≥50 years), respectively. Univariate and multivariate analyses identified only high level of CCI (≥2 or more) as an independent risk factor for subsequent development of EOC in women after ovarian surgery for benign ovarian tumors (HR 59.17, 95% CI 7.50-466.80 in women with CCI level of 2 and HR 190.68, 95% CI 24.33-2494.19, in women with CCI level ≥3, respectively). Conclusion: Our results, if confirmed, suggest that women with other comorbidities (CCI) should be well informed that they may have a higher risk of subsequent development of EOC when ovarian surgery is planned even though the final pathology showed a benign ovarian tumor.

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Infertility and mortality

Cited by 39 publications

References 45 publications

High-sensitivity C-reactive protein is not independently associated with self-reported infertility in National Health and Nutrition Examination Survey 2015–2018 data

High-sensitivity C-reactive protein is not independently associated with self-reported infertility in National Health and Nutrition Examination Survey 2015–2018 data

The Effect of Copper Oxide and Selenium Nanoparticles on Vitamin D Levels in Women With Infertility

<p>Subsequent Development of Epithelial Ovarian Cancer After Ovarian Surgery for Benign Ovarian Tumor: A Population-Based Cohort Study</p>

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