Inflammatory Bowel Disease: Impact on Scores of Quality of Life, Depression and Anxiety in Patients Attending a Tertiary Care Center in Brazil

Calixto, Raquel; Flores, Cristina; Francesconi, Carlos Fernando de Magalhães

doi:10.1590/s0004-2803.201800000-54

Cited by 15 publications

(28 citation statements)

References 39 publications

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“…The analysis of the IBDQ showed that 70% of the patients rated their QOL as "good" or "very good", with an average of 157.9 points and standard deviation of ±41.7 points, presenting correlation with current studies, such as Francesconi et al (1) , who obtained an average of 152.7 and 160.9 points, with standard deviation ranging from ±39.3 to 46.9 for CD and URC, respectively. Although patients with IBD from different locations present similar scores, they have lower results when compared to the general population.…”

Section: Resultssupporting

confidence: 64%

“…IBD have a bimodal characteristic, with incidence in young adults and later in those over 50 years of age. The results of the study showed higher incidence in females (73.2%), CD diagnosis (63%), and an average age of patients 46.5 years, slightly above when compared with some studies (1)(2)(3)(4)(5)(6)(7)(8)(9) and the regional study of scores. These significant findings allow to establish the correlation between the two methods analyzed, being good indicators of QOL in patients with IBD.…”

Section: Discussionmentioning

confidence: 45%

“…Inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative rectocolitis (URC) are all chronic pathologies with varied clinical manifestations. They differ according to the predominant location of the lesions and their extent, the presence or absence of systemic manifestations and complications of the disease, provoking intestinal and extraintestinal symptoms (1)(2) .…”

Section: Introductionmentioning

confidence: 99%

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Quality of Life of Patients From a Multidisciplinary Clinic of Inflammatory Bowel Disease

Ficagna

Dalri

Malluta

et al. 2020

Arq. Gastroenterol.

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BACKGROUND: Inflammatory bowel disease encompasses pathological entities, the main being Crohn’s disease and ulcerative rectocolitis. Both are characterized by chronic inflammation of the intestine. It affects young people of active age, compromising the situation of those patients, especially their quality of life, experiencing a strong deterioration in their clinical condition, from physical to social and emotional aspects. OBJECTIVE: Evaluate the quality of life of patients assisted in the multidisciplinary reference outpatient clinic for the treatment of inflammatory bowel diseases, through sociodemographic data and specific questionnaires on the disease, evaluating the intestinal and systemic symptoms and the social and emotional aspects. Make a comparison between the two scales used to obtain the data. METHODS: A cross-sectional study was carried out in which patients diagnosed with inflammatory bowel disease were evaluated and observed at a reference outpatient clinic for treatment from May 2017 through December 2018. The participants responded to the Socio-demographic and Clinical Protocol, the SF-36 general quality of life questionnaire and the specific Inflammatory Bowel Disease questionnaire, in addition the correlation between the two scales was performed using Pearson’s Correlation (metric scale), which data were analyzed by means of descriptive statistics and the significance level adopted was 5% (P≤0.05). The population studied consisted of 71 patients, excluding pregnant or nursing women and patients under 18 years of age. RESULTS: Seventy-one patients participated in the study, with an average age of 46.5 years and standard deviation of ±13.8; 45 patients had Crohn’s disease and 26 were diagnosed with ulcerative rectocolitis; 73.2% were women; 64.8% married; 8.4%, smokers; 50.7% reported practising some type of physical activity. A good distribution of patients was observed between the domains of each questionnaire; no low scores were found for quality of life, and systemic symptoms and emotional aspects were those with the lowest scores among the parameters of the Inflammatory Bowel Disease Questionnaire; physical (40.6±44.4) and emotional aspects (49.5±46.0) had lower scores among the Short Form-36 domains. The correlation between the two questionnaires proved to be significant. CONCLUSION: The clinical profile of the patients followed the characteristics of distribution and prevalence of these diseases. The impact of diseases on quality of life was observed in several aspects, especially those related to psychological components. Multidisciplinary follow-up, as well as psychological, social, nutritional and educational support should be considered important determinants to maintain or improve the quality of life of these patients.

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Section: Resultssupporting

confidence: 64%

Section: Discussionmentioning

confidence: 45%

Section: Introductionmentioning

confidence: 99%

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Quality of Life of Patients From a Multidisciplinary Clinic of Inflammatory Bowel Disease

Ficagna

Dalri

Malluta

et al. 2020

Arq. Gastroenterol.

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“…Some studies, based on the use of the HADS questionnaire, supported the idea that keeping patients in remission has a positive impact on quality of life by reducing levels of depression. However, our results suggest that IBD patients experience concern and apprehension during periods of remission as well, probably due to the unpredictability of the course of the disease and the fear of complications [45]. Therefore, it is quite important to provide and maintain psychological care also for patients in remission, without underestimating this delicate issue [46].…”

Section: Discussionmentioning

confidence: 81%

The Reality of Patient-Reported Outcomes of Health-Related Quality of Life in an Italian Cohort of Patients with Inflammatory Bowel Disease: Results from a Cross-Sectional Study

Larussa

Abenavoli

Boccuto

et al. 2020

JCM

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Inflammatory bowel disease (IBD) has a negative impact on patients’ physical and psychological well-being, social performance, and working capacity, thereby worsening their health-related quality of life (HRQoL). Clinicians should take care of the patients’ global health, including the psychological, social, and emotional spheres. We aimed to investigate the reality of patient-reported outcomes of HRQoL in a series of IBD patients. Consecutive Crohn´s disease (CD) and ulcerative colitis (UC) patients in clinical remission were recruited. The survey consisted of the Short Inflammatory Bowel Disease Questionnaire (S-IBDQ), the Hospital Anxiety and Depression Scale (HADS), the Brief Illness Perception Questionnaire (B-IPQ), and a questionnaire dealing with impact of IBD on patients’ lives. Demographic and clinical characteristics were recorded. Of 202 participants (29% CD and 71% UC; 54% male; median age 48 years; mean disease duration 14 ± 11 years), 52% had poor HRQoL, 45% anxiety/depression, and 35% sleep disturbance and a high perception of disease (mean score 42.8 ± 14.3). In the multivariate analysis, a low HRQoL was rather associated with UC than CD (p = 0.037), IBD surgery (p = 0.010), disease duration (p = 0.01), sleep disturbance (p = 0.014), anxiety/depression (p = 0.042), and high illness perception (p = 0.006). IBD affected working performance and social activities in 62% and 74% of patients, respectively. Satisfaction regarding quality of care, biologics, and surgery approach were claimed in 73%, 69%, and 76% of patients, respectively. Although 84% of patients trusted their gastroenterologist, only 66% of them discussed IBD impact on HRQoL during visit. In a series of IBD patients in remission, the low HRQoL was significantly associated with surgery, disease duration, sleep disturbance, anxiety/depression, and high illness perception. Even though patients were satisfied with the quality of their care, it appears that clinicians should pay more attention to patients’ emotional status.

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“…In addition to physical impairments, CD patients experience reduced health-related quality of life (QoL) [ 5 , 6 ], a negative body image (BI) and lower self-esteem (SE) [ 7 – 9 ], which negatively affect their social-psychological well-being. Few studies, however, have assessed the social and psychological effects experienced by CD patients with PF.…”

Section: Introductionmentioning

confidence: 99%

Infliximab for Crohn’s Disease Patients with Perianal Fistulas: Better Image, Better Life

et al. 2020

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Background Patients with Crohn’s disease (CD) experience physical impairments, poor quality of life and negative body image. These factors are exacerbated in CD patients with active perianal fistulas. Material/Methods Baseline characteristics were compared in retrospectively enrolled CD patients with and without active perianal fistulas. The relationships between improvements in perianal fistulas and quality of life, body image, and self-esteem were determined. The effects of infliximab treatment on improvement of psychological-social status were assessed in CD patients with active perianal fistulas. Results Of the 301 CD patients included in our institution’s database. 91 (30.2%) had active perianal fistulas. After adjustment by propensity score matching, CD patients with active perianal fistulas had lower self-esteem and more severe body image dissatisfaction than CD patients without active perianal fistulas (P<0.01 each). Perianal fistula response was closely associated with improvements in quality of life, body image dissatisfaction and self-esteem (P<0.01 each). Patients with perianal fistula treated with infliximab showed a response rate of 68.3%, significantly higher than the rate in patients with perianal fistula not treated with infliximab (P=0.005). Furthermore, improvements of life quality, body image and self-esteem were significantly greater in patients with perianal fistula who were than were not treated with infliximab (P<0.05 each). Conclusions CD patients with active perianal fistulas experience body image dissatisfaction, low self-esteem and poor quality of life. Treatment of these patients with infliximab could improve their body image, self-esteem and quality of life.

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Inflammatory Bowel Disease: Impact on Scores of Quality of Life, Depression and Anxiety in Patients Attending a Tertiary Care Center in Brazil

Cited by 15 publications

References 39 publications

Quality of Life of Patients From a Multidisciplinary Clinic of Inflammatory Bowel Disease

Quality of Life of Patients From a Multidisciplinary Clinic of Inflammatory Bowel Disease

The Reality of Patient-Reported Outcomes of Health-Related Quality of Life in an Italian Cohort of Patients with Inflammatory Bowel Disease: Results from a Cross-Sectional Study

Infliximab for Crohn’s Disease Patients with Perianal Fistulas: Better Image, Better Life

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