Inflammatory Linear Verrucose Epidermal Nevus

Altman, Jules; Mehregan, Amir H.

doi:10.1001/archderm.1971.04000220043008

Cited by 136 publications

(77 citation statements)

References 2 publications

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“…The present case fulfils all criteria as formulated by Altman and Mehregan [2] except for 'predominance of the left lower extremity'. This predominance, however, could not be confirmed by other groups [5,[9][10][11][12][13], Various treatments which have been suggested to exert a positive effect in ILVEN are summarized in table 1.…”

Section: Discussionsupporting

confidence: 74%

“…It was first described by Unna in 1896 [ 1 ]. In 1971. the criteria for the diagnosis of ILVEN have been defined by Altman and Mehregan [2]: early age of onset; 4:1 predominance in females; fre quent involvement of the left lower extremity; pruritus; distinctive inflammatory and psoriasiform histologic appearance; persistent lesions showing marked refracto riness to treatment.…”

mentioning

confidence: 99%

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Treatment of Inflammatory Linear Verrucous Epidermal Nevus

Rulo

Kerkhof²

1991

Dermatology

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Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare and chronic skin disorder, which may trouble the patient considerably. The condition is generally believed to be resistant to therapy, although some authors have reported success with several treatments, including dithranol and etretinate. The present case, a classical presentation of ILVEN, again illustrates the refractoriness to various treatments, including an experimental treatment with topical 13-cis-retinoic acid. A review of the literature on therapeutic possibilities of ILVEN is presented. Based on our own observations and literature data, it is attractive to hypothesize that a positive result with treatments such as dithranol and retinoids should be interpreted as an antipsoriatic effect in ILVEN with superimposed psoriasis.

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Section: Discussionsupporting

confidence: 74%

mentioning

confidence: 99%

Treatment of Inflammatory Linear Verrucous Epidermal Nevus

Rulo

Kerkhof²

1991

Dermatology

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“…Linear ncurodcrmatiis Table 2) were outlined by Altman and Mehregan in 1971 [4]: (1) erythcmato-desquamative papules with a verrucose surface and a tendency to group in bands or plaques;…”

Section: Discussionmentioning

confidence: 99%

“…The histological characteristic of ILVEN [5,22] is a regular alternation of parakeratotic areas with absence of the granular layer and other hyperkeratotic areas with thiekened granular layer; on the other hand, data have been found of unspecific chronic dermatitis [4,5,22] (psoriasiform, cczematiform), which was first described by Unna [3] in 1896. It has recently been reported that linear epidermic nevi may also show lichenoid histology [23].…”

Section: Discussionmentioning

confidence: 99%

Congenital linear psoriasis: case report and differences with ILVEN

Loòpez‐Avila

Diíaz

Vicente

et al. 1994

Acad Dermatol Venereol

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We report the case of a 5-year-old child who from birth had five erythemato-desquamative papulous lesions with a verrucose surface and linear distribution in the proximal region of the lower left leg not following the lines of Blashko. The morphological aspect and the evolution of the lesions, data from physical exploration of the skin and adnexa, the characteristics of the histopathology and its association with HLA Cw6 led us to diagnose congenital linear psoriasis. Differential diagnosis was established basically with ILVEN since distinction between the two entities is now traditional. We took into consideration the fact that linear psoriasis is a particular entity and can occur eongenitaliy, as in the case reported; although this is an exceptional occurrence.

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“…In addition to displaying varying stages of epidermal differentiation, the histopathology of epidermal nevi may mimic other clinical entities such as seborrheic keratosis (2), acanthosis nigricans (3), Darier's disease (acantholytic dyskeratosis) (4,5), buUous ichthyosis (epidermolytic hyperkeratosis) (6,7), porokeratosis (8), comedonal acne (9), and psoriasis, eczematous dermatitis, or lichen simplex chronicus (10). Furthermore, a nevus may exhibit more than one histopathologic pattem in different topographic sites or at different times (1).…”

mentioning

confidence: 99%

Histologic Changes Resembling the Vernicous Phase of Incontinentia Pigmenti Within Epidermal Nevi: Report of Two Cases

Fletcher

Williams

Lane

1985

Pediatric Dermatology

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A wide spectrum of histopathologic changes has been reported to occur within epidermal nevi. We saw two patients with warty nevoid lesions in which histopathologic features of incontinentia pigmenti, verrucous phase, were present. The diagnosis of incontinentia pigmenti was excluded because both patients were male, lacked a preceding vesicular stage, and did not demonstrate other features of the disorder.

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Inflammatory Linear Verrucose Epidermal Nevus

Cited by 136 publications

References 2 publications

Treatment of Inflammatory Linear Verrucous Epidermal Nevus

Treatment of Inflammatory Linear Verrucous Epidermal Nevus

Congenital linear psoriasis: case report and differences with ILVEN

Histologic Changes Resembling the Vernicous Phase of Incontinentia Pigmenti Within Epidermal Nevi: Report of Two Cases

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