Inflammatory Pseudotumor in the Nasal Cavity and Sinuses: A Case Report and Associated Literature Review

Li, Jing; Wang, Maohua; Li, Wangwei; Tao, Yuejin; Shi, Xiaoyan

doi:10.1177/0145561320924489

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…While corticosteroid therapy can significantly shrink the tumor size, but there are not enough follow-up data yet so as to confirm its efficacy. 1…”

Section: Discussionmentioning

confidence: 99%

“…IPT might be secondary to autoimmune dysfunction, smoking, trauma, vasculitis, foreign bodies, fibroblastic proliferation, acute infection response and reparative process of post-inflammation. 1 Mycoplasmata, mycobacteria, Rhodococcus equi, Klebsiella rhinoscleromatis, nocardiae, actinomycetes, Epstein-Barr virus, Herpes simplex 8 have been implicated in pathologic specimens. 2,3 Interleukin 1 contributes to the systemic and local effects of IPT.…”

Section: Introductionmentioning

confidence: 99%

“…2 IP is usually positive for vimentin, EMA, CD138, CD20, CD68, and negative for S100 in immunohistochemical staining. 1 Patients present with fever, weight loss, hypergammaglobulinemia, growth retardation, thrombocytosis, iron deficiency anemia, symptoms related to mass effect, or a combination of these. Differential diagnosis includes carcinoma, fibrodysplastic lesions, lymphoma, chronic fungal infection, Wegener's granulomatosis, extramedullary plasmacytoma.…”

Section: Introductionmentioning

confidence: 99%

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Inflammatory pseudotumour of nasal cavity and sinuses: a case report with review of literature

Sharma,

Urangia

2024

Int J Res Med Sci

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Inflammatory pseudotumor (IPT) is a benign non-neoplastic rare mass lesion clinically and radiologically simulating neoplasm thus generally requiring a biopsy to exclude malignancy. It occurs almost anywhere all over the body with most common locations being lungs and orbit with only 15% of it occurs in head and neck non-orbital region. Here we are described a case of 52-year-old female patient having bleeding from left nostril with swelling, redness of left side of nose and face, initially painless. Radiological imaging was highly suspicious of malignancy. HPE showed inflammatory lesions. The fungal culture report of nasal specimen was showing ‘no growth’. Blood examination was within normal limits; blood sugar levels was within normal limits. Systemic steroids were started which showed drastic improvements. Most of the IPTs in head and neck region shows a benign course, but cases related to paranasal sinuses seems to be of highly aggressive behaviour, with poor response to surgery, chemotherapy, radiotherapy; showing recurrences and fatal outcome. In such cases corticosteroid therapy generally shows good outcome. Tumors for which complete resection would result in morbidity may be treated with corticosteroids conservatively and close follow up. Understanding of natural history and pathophysiologic features of IPTs is helpful in differential diagnosis and may prevent unnecessary surgeries.

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“…While corticosteroid therapy can significantly shrink the tumor size, but there are not enough follow-up data yet so as to confirm its efficacy. 1…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Inflammatory pseudotumour of nasal cavity and sinuses: a case report with review of literature

Sharma,

Urangia

2024

Int J Res Med Sci

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The role of endoscopic medial maxillectomy in sinus disease

Govindaraju

Prepageran²

2020

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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Purpose of review The endoscopic medial maxillectomy (EMM) has remained a relevant procedure for certain sinus diseases and at the same time reemerged as a salvage technique or even as a primary procedure for other diseases. Several mucosal-sparing techniques have also been described and the outcome of the surgeries is available for review. Recent findings Modifications of the EMM technique in the last two decades, aimed at mucosal preservation of the inferior turbinate, nasolacrimal duct, and medial maxillary wall have been successful in addressing a multitude of diseases. There are also evidences to support adjunct procedures/methods to improve access, healing, and to address associated dysfunction such as impaired mucociliary clearance. Tailored approaches have shown favourable outcomes with a low rate of adverse effects. Summary The EMM is appropriate for selected indications, in particular lesions causing medial wall destruction or extensive tumour involving the anterior wall or the prelacrimal recess. As for other maxillary sinus diseases including those identified to a limited site, a modified EMM is a reasonable consideration. The choice is appropriate provided instrument access, visualization, the ability for complete resection, postoperative care, and the requirement for surveillance is not compromised. A tailored approach with or without adjunct procedures is recommended.

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Inflammatory Pseudotumor in the Nasal Cavity and Sinuses: A Case Report and Associated Literature Review

Cited by 2 publications

References 19 publications

Inflammatory pseudotumour of nasal cavity and sinuses: a case report with review of literature

Inflammatory pseudotumour of nasal cavity and sinuses: a case report with review of literature

The role of endoscopic medial maxillectomy in sinus disease

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