Infliximab does not increase postoperative complication rates in patients with Crohn's disease

Marchal, Ludwig; D’Haens, Geert; Assche, Gert Van; Hiele, Martin; D’Hoore, André; Penninckx, Freddy; Rutgeerts, Paul

doi:10.1016/s0016-5085(03)81038-7

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Biological Therapies1

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2011

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“…No clinical trial has addressed complications after orthopedic surgery in RA patients receiving biological treatments, but there have been some retrospective studies. Bibbo et al (11) investigated the influence of infliximab and etanercept in orthopedic surgery and concluded that they could be administered safely in the perioperative period without increasing the risk of infectious or wound-healing complications. However, the pathologic study of the wounds is not reported, and the authors do not describe how they assessed wound-healing delay or bone-healing complications, two key variables in their study.…”

Section: Biological Therapiesmentioning

confidence: 99%