Influence of Deep Breathing on Heart Rate Variability in Parkinson’s Disease: Co-relation with Severity of Disease and Non-Motor Symptom Scale Score

Bidikar, Mukta P

doi:10.7860/jcdr/2014/9470.4550

Cited by 5 publications

(4 citation statements)

References 24 publications

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“…Other possibilities include systems which are not associated with movement, such as mindfulness-based cognitive therapy (MBCT) [ 79 ], meditation [ 80 ], breathing techniques [ 81 ], hypnosis [ 82 , 83 ] and biofeedback [ 84 ].…”

Section: Resultsmentioning

confidence: 99%

The Mechanism of Physical Activity-induced Amelioration of Parkinson’s Disease: A Narrative Review

Gronek¹,

Haas²,

Czarny³

et al. 2021

Aging and disease

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Section: Resultsmentioning

confidence: 99%

The Mechanism of Physical Activity-induced Amelioration of Parkinson’s Disease: A Narrative Review

Gronek¹,

Haas²,

Czarny³

et al. 2021

Aging and disease

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“…PD is multifactorial with many features exhibiting diurnal fluctuations, such as thermoregulation disorders, circadian variation of blood pressure and heart rate, emotional dysregulation, and even reactions to anti-PD pharmacotherapy that manifest as abnormalities in rhythm [ 3 , 19 – 23 ]. Particularly, motor activity can vary throughout the day [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson’s Disease

Fan

Luo

et al. 2018

Parkinson's Disease

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Background The clock genes controlling biological rhythm play an important role in the pathophysiology of aging. The purpose of this study was to determine whether there is an association between a variant of the circadian locomotor output cycles kaput (CLOCK) gene and circadian dysfunction of Parkinson's disease (PD). Methods Six hundred and forty-six cases of Parkinson's disease from consecutive outpatients and inpatients ward from our hospital were included in this study. Kompetitive allele-specific PCR was used to determine the frequency distribution of genotypes and alleles. The examinations for the PD group were assessed in person in order to evaluate motor symptoms, cognitive function, sleep, and depression, including the Unified Parkinson's Disease Rating Scale (UPDRS), Mini-Mental State Examination (MMSE), Pittsburgh Sleep Quality Index (PSQI), and 17-item Hamilton Rating Scale for Depression (HAMD-17). Results Motor fluctuation (P < 0.001) and sleep disorders (P=0.007) were significantly different between the two groups. These correlations persisted after adjusting for confounding risk factors by further binary logistic regression analysis, suggesting that the CLOCK 3111T/C variant was associated with motor fluctuation (OR = 1.080, P < 0.001) and a subjective sleep disorder (OR = 1.130, P=0.037). Conclusion The CLOCK 3111T/C variant can be an independent risk factor for motor fluctuation and sleep disorder in Parkinson's disease.

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“…1 The age of onset is in the 60s (range: 35-85 years), and the course of the illness ranges between 10 and 25 years encompassing both motor and non-motor symptoms. 2 PD has been traditionally perceived as a motor disorder. However, several non-motor symptoms have gained attention in recent years, including autonomic, sensory, neuropsychiatric and cognitive dysfunction.…”

Section: Introductionmentioning

confidence: 99%

“…1 The age of onset is in the 60s (range: 35–85 years), and the course of the illness ranges between 10 and 25 years encompassing both motor and non-motor symptoms. 2 …”

Section: Introductionmentioning

confidence: 99%

Effect of Disease Severity on Respiratory Impedance in Parkinson’s Disease

Sampath

Srivastava

Goyal

et al. 2020

Annals of Neurosciences

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Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder. PD has been traditionally perceived as a motor disorder. However, it is frequently associated with pulmonary dysfunction which has been assessed by Spirometry, an effort-dependent technique. Purpose: To evaluate in patients with PD the effect of disease severity on respiratory impedance using Impulse Oscillometry (IOS) and to correlate with Spirometry. Methods: The study was conducted on 30 patients diagnosed with PD. Pulmonary function was assessed by IOS and spirometer. IOS is an effort-independent technique that uses sound waves of different frequencies to measure airway resistance. Spirometer measures the lung volume and generates flow–volume and volume–time relationship. Results: The mean age of patients was 60.1±9.45. Resistance at 5 Hz (R5) was found to be negatively correlated with forced expiratory volume in the first second of the FVC manoeuver (FEV1) ( r = –0.628, P = .002), FEV1/FVC (forced vital capacity) ( r = –0.487, P = .025), and PEF ( r = –0.599, P = .004), and resistance at 20 Hz (R20) with FEV1 ( r = –0.474, P = .029) and PEF ( r = –0.522, P = .015). There was significant increase in R5 (0.32(0.36–0.28) vs 0.47(0.60–0.36); P = .04) and R20 (0.25(0.28–0.20) vs 0.30(0.40–0.25); P = .04) in stage II as compared to stage I of Hoehn–Yahr scale. Conclusion: IOS might be a promising tool for diagnosis of respiratory dysfunction in addition to Spirometry, especially in cases where patients are not able to perform forced manoeuvers.

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Influence of Deep Breathing on Heart Rate Variability in Parkinson’s Disease: Co-relation with Severity of Disease and Non-Motor Symptom Scale Score

Abstract: Abnormalities of autonomic function and NMS were integral and present across all the stages of PD patients. Early recognition and treatment of these may decrease morbidity and improve quality of life of PD patients.

Cited by 5 publications

References 24 publications

The Mechanism of Physical Activity-induced Amelioration of Parkinson’s Disease: A Narrative Review

The Mechanism of Physical Activity-induced Amelioration of Parkinson’s Disease: A Narrative Review

CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson’s Disease

Effect of Disease Severity on Respiratory Impedance in Parkinson’s Disease

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