Mineral nutrient are used in countless metabolic pathways in dairy cow's body, and even some mineral deficiency can result in cow's suboptimal performance. To study the effect of season mineral constituents of cattle, 20 cows were taken, out of which, 10 animals in lactation stage (peak and mid lactation) and 10 in dry period. The study was carried out in and around Rajnandgaon district of Chhattisgarh state. A total 15 ml of blood was collected from each animals analyzed for mineral constituents during different seasons. The data was statistically analyzed to draw the conclusion the average value of calcium, potassium, sodium, iron was high in summer. While, the average magnesium and copper values were higher in rainy and winter season respectively. Average serum iron was lower in dry period. Seasonal variation of serum concentration was non significant. Lactation stage had no significant effect on mineral constituents. Sodium, iron,copper were slightly lower in dry period. The present investigation revealed that mineral constituents of animals varied with season and indicates further scope of manage mental interventions in feeding of animal according to different season.