Influence of ethanol as bore fluid component on the morphological structure and performance of PES hollow fiber membrane for oil in water separation

Otitoju, Tunmise Ayode; Ahmad, Abdul Latif; Ooi, Boon Seng

doi:10.1007/s11814-017-0189-8

Cited by 12 publications

(3 citation statements)

References 43 publications

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“…This is not unprecedented as EtOH has shown hollow fiber swelling and impact on permeability in other industrial applications. [ 22,23 ]…”

Section: Resultsmentioning

confidence: 99%

“…This is not unprecedented as EtOH has shown hollow fiber swelling and impact on permeability in other industrial applications. [22,23] To assess the EtOH rejection coefficient, the batch process was assessed with the Equation (1) model. Using an inline density measurement on the permeate, the EtOH concentration was calculated across the diavolumes.…”

Section: Batch Processmentioning

confidence: 99%

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Impact of ethanol on continuous inline diafiltration of liposomal drug products

Worsham

Thomas

Farid

2023

Biotechnology Journal

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Liposomal drug products are playing an increasing role in the field of drug delivery. With this increased demand comes the need to increase the capabilities and capacity of manufacturing options. Continuous manufacturing techniques present a significant opportunity to address these needs for liposomal manufacturing processes. Liposomal formulations have unique considerations that impact translation from batch to continuous process designs. This article examines aspects of converting to a continuous design that were previously viewed as inconsequential in a batch process. The batch process involves the removal of ethanol through tangential flow filtration (TFF). Ethanol was found to reduce the permeability of the hollow fibers used for TFF. This effect was determined to have minimal impact on the overall batch process design but considerable influence on the design of continuous TFF such as inline diafiltration (ILDF). Using a pilot scale setup, ethanol was found to decrease permeability in an inverse manner to ethanol concentration. Further assessment found that dilution of the ethanol levels prior to diafiltration can significantly reduce the amount of ILDF stages needed and that a continuous design requires less buffer to the commensurate batch design.This article is protected by copyright. All rights reserved

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“…This is not unprecedented as EtOH has shown hollow fiber swelling and impact on permeability in other industrial applications. [ 22,23 ]…”

Section: Resultsmentioning

confidence: 99%

Section: Batch Processmentioning

confidence: 99%

Impact of ethanol on continuous inline diafiltration of liposomal drug products

Worsham

Thomas

Farid

2023

Biotechnology Journal

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“…First, a lower roughness means less HA adsorption. Second, It has been well established that a more hydrophilic membrane will have a lower fouling tendency [50,51]. A membrane with a better hydrophilic character will weaken the hydrophobic interaction between the membrane surface and the foulant, enabling the foulant that is adsorbed on membrane surface to be easily washed away using hydraulic method of cleaning.…”

Section: Membrane Fouling Analysismentioning

confidence: 99%

Removal of Humic Acid Using 3-Methacryloxypropyl Trimethoxysilane Functionalized MWCNT Loaded TiO2/PES Hybrid Membrane

et al. 2021

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In the present work, a highly efficient mixed matrix membrane (MMM) for humic acid (HA) removal was developed. Multiwalled carbon nanotubes (MWCNTs) were functionalized in the presence of 3-methacryloxypropyl trimethoxysilane using the co-condensation method and were subsequently loaded with TiO2 (prepared via the sol–gel route). The as-prepared material was then incorporated into a PES polymer solution to prepare a fMWCNT-TiO2/PES hybrid membrane via non-solvent induced phase inversion. The microstructure of the membrane was characterized using Fourier transform infrared spectroscopy, atomic force microscopy, scanning electron microscopy, water contact angle, thickness, porosity, and pore size. The fMWCNT-TiO2/PES hybrid membrane was tested for the removal of HA and antifouling performance. The results show that the surface hydrophilicity of the membranes was greatly improved upon the addition of the fMWCNT-TiO2 particles. The results show that 92% of HA was effectively removed after 1 h of filtration. In comparison with pristine membrane, the incorporation of fMWCNT-TiO2 nanoparticles led to enhanced pure water flux (99.05 L/m2 h), permeate flux (62.01 L/m2 h), higher HA rejection (92%), and antifouling improvement (RFR: 37.40%, FRR: 86.02%). Thus, the fMWCNT-TiO2/PES hybrid membrane is considered to be a great potential membrane for the improvement of ultrafiltration membranes.

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Fabrication and applications of polyethersulfone hollow fiber membranes

Feng

Chung

2021

Hollow Fiber Membranes

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Influence of ethanol as bore fluid component on the morphological structure and performance of PES hollow fiber membrane for oil in water separation

Cited by 12 publications

References 43 publications

Impact of ethanol on continuous inline diafiltration of liposomal drug products

Impact of ethanol on continuous inline diafiltration of liposomal drug products

Removal of Humic Acid Using 3-Methacryloxypropyl Trimethoxysilane Functionalized MWCNT Loaded TiO2/PES Hybrid Membrane

Fabrication and applications of polyethersulfone hollow fiber membranes

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