Influence of pH on interaction of silver nanoparticles - protein: Analyses by spectroscopic and thermodynamic ideology

Siddiq, A. Mohammed; Murugan, D.; Srivastava, R. S.; Alam, Md. Sayem

doi:10.1016/j.colsurfb.2019.110524

Cited by 27 publications

(10 citation statements)

References 43 publications

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“…Our studies showed that at pH 8.3 α-helix decreases in the case of silver ions and increases in the case of silver nanoformulation S7. The results obtained by Siddiq et al (2019) may suggest that more silver ions are related to HSA than silver nanoformulations (S7) (pI HSA and BSA are the same, equal to 4.7). Reymond-Laruinaz et al (2016) in their studies confirmed the interaction of silver nanoparticles with proteins (including BSA).…”

Section: Discussionmentioning

confidence: 95%

“…The samples S2 and S7 differ from each other in size, compounds, surface area and bioavailability ( Kędziora et al, 2020 ). Moreover, it should be added that environmental conditions (e.g., pH, chemical composition, temperature) determine the physico-chemical properties of nanomaterials and their behavior ( Pareek et al, 2018 ; Siddiq et al, 2019 ). While the antibacterial mode of action (MoA) of silver ions is well defined and includes membrane disruption, ROS generation, molecules (such as protein, nucleic acids) inactivation, other studies confirm the various MoA after exposure to silver nanomaterials ( Pareek et al, 2018 ; Bonilla-Gameros et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

“…The environmental conditions may be a separate cause of the interaction of silver nanoformulations with proteins. Siddiq et al (2019) investigated the effect of the pH of the medium and behavior of silver nanoparticles with bovine serum albumine (BSA) using the CD technique. They concluded that α-helix decreased by increasing the AgNP concentration, and the basic medium fosters aggregation of silver nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

“…The mode of the antibacterial activity of silver ions and the mechanism of bacterial resistance to them have been well described in the literature ( Pareek et al, 2018 ; Bonilla-Gameros et al, 2020 ). There are also many attempts to explain how SNF work, but the results can be conflicting ( Li et al, 1997 ; Banerjee et al, 2010 ; Liu et al, 2012 ; Radzig et al, 2013 ; Randall et al, 2015 ; Borkowski et al, 2016 ; Reymond-Laruinaz et al, 2016 ; Zhang et al, 2018 ; Zheng et al, 2018 ; Anuj et al, 2019 ; Siddiq et al, 2019 ; Wu et al, 2019 ). SNF can interact with the bacterial membrane, cell wall or subcellular structure, causing their damage or function disruption (through generations of reactive oxygen species (ROS) or affinity toward intracellular structure) in different ways than silver ions, and differences between individual SNF forms might also be observed ( Pareek et al, 2018 ; Zheng et al, 2018 ; Kędziora et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Antibacterial Mode of Action of Silver Ions and Silver Nanoformulations With Different Physico-Chemical Properties: Experimental and Computational Studies

et al. 2021

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The aim of this study was to compare the antibacterial mode of action of silver ions (Ag+) and selected silver nanoformulations against E. coli strains (E. coli J53, Escherichia coli BW25113 and its derivatives: Δ ompA, Δ ompC, Δ ompF, Δ ompR, ompRG596AcusSG1130A, cusSG1130A). In this research we used various experimental methods and techniques such as determination of the minimal inhibitory concentration, flow cytometry, scanning electron microscopy, circular dichroism as well as computational methods of theoretical chemistry. Thanks to the processing of bacteria and silver samples (ions and nanoformulations), we were able to determine the bacterial sensitivity to silver samples, detect reactive oxygen species (ROS) in the bacterial cells, visualize the interaction of silver samples with the bacterial cells, and identify their interactions with proteins. Differences between the mode of action of silver ions and nanoformulations and the action of nanoformulations themselves were revealed. Based on the results of computational methods, we proposed an explanation of the differences in silver-outer protein interaction between silver ions and metallic silver; in general, the Ag0 complexes exhibit weaker interaction than Ag+ ones. Moreover, we identified two gutter-like areas of the inner layer of the ion channel: one more effective, with oxygen-rich side chains; and another one less effective, with nitrogen-rich side chains.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparison of Antibacterial Mode of Action of Silver Ions and Silver Nanoformulations With Different Physico-Chemical Properties: Experimental and Computational Studies

et al. 2021

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“…Multiscale CG modeling of protein adsorption on a silver nanoparticle. Thermodynamics and kinetics of protein adsorption process onto pristine AgNP have been previously addressed for various blood plasma, milk, and other dietary proteins 79,80,89,90,[81][82][83][84][85][86][87][88] : e.g. bovine (BSA, PDBID: 3V03) and human (HSA, PDBID:1AO6) serum albumins, bovine (BHb, PDBID: 1FSX) and human (HHb, PDBID: 1GZX) hemoglobin, papain (PDBID: 9PAP), bromelain (PDBID:1W0Q), lysozyme (PDBID: 1AKI), and bovine lactoferrin (BLf, PDBID:1BLF).…”

Section: Resultsmentioning

confidence: 99%

Multiscale modeling of bio-nano interactions of zero-valent silver nanoparticles.

Subbotina

Lobaskin

2021

Preprint

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Understanding the specifics of interaction between protein and nanomaterial is crucial for designing efficient, safe, and selective nanoplatforms, such as biosensor or nanocarrier systems. Routing experimental screening for the most suitable complementary pair of biomolecule and nanomaterial used in such nanoplatforms might be a resource-intensive task. While a variety of computational tools is available for pre-screening libraries of small drug molecules interacting with proteins, options for high-throughput screening of protein libraries for binding affinities to new and existing nanomaterials are limited. In the current work, we present the results of a systematic computational study of protein interaction with zero-valent silver nanoparticles using a multiscale approach. A variety of blood plasma and dietary proteins, namely, bovine and human serum albumins, bovine and human hemoglobin, papain, bromelain, lysozyme, and bovine lactoferrin, were examined. Selected combinations of nanomaterial and proteins can serve as a starting model for developing noble metal-based nanocarriers and biosensors. The computed binding (adsorption) characteristics for selected proteins were validated by experimental data reported in the literature. An advanced in silico nano-QSAR/QSPR interfacial descriptor 〖log⁡P〗^NM was also introduced to characterize the relative hydrophobicity/hydrophilicity of the nanomaterial.

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Multifunctional Self‐Assembled Bio‐Interfacial Layers for High‐Performance Zinc Metal Anodes

Lu,

Wang,

Yang

et al. 2024

Angewandte Chemie

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Rechargeable aqueous zinc‐ion (Zn‐ion) batteries are widely regarded as important candidates for next‐generation energy storage systems for low‐cost renewable energy storage. However, the development of Zn‐ion batteries is currently facing significant challenges due to uncontrollable Zn dendrite growth and severe parasitic reactions on Zn metal anodes. Herein, we report an innovative strategy to improve the performance of aqueous Zn‐ion batteries by leveraging the self‐assembly of bovine serum albumin (BSA) into a bilayer configuration on Zn metal anodes. BSA's hydrophilic and hydrophobic fragments form unique and intelligent ion channels, which regulate the migration of Zn ions and facilitate their desolvation process, significantly diminishing parasitic reactions on Zn anodes and leading to a uniform Zn deposition along the Zn (002) plane. Notably, the Zn||Zn symmetric cell with BSA as the electrolyte additive demonstrated a stable cycling performance for up to 2400 hours at a high current density of 10 mA cm‐2. This work demonstrates the pivotal role of self‐assembled protein bilayer structures in improving the durability of Zn anodes in aqueous Zn‐ion batteries.

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Influence of pH on interaction of silver nanoparticles - protein: Analyses by spectroscopic and thermodynamic ideology

Cited by 27 publications

References 43 publications

Comparison of Antibacterial Mode of Action of Silver Ions and Silver Nanoformulations With Different Physico-Chemical Properties: Experimental and Computational Studies

Comparison of Antibacterial Mode of Action of Silver Ions and Silver Nanoformulations With Different Physico-Chemical Properties: Experimental and Computational Studies

Multiscale modeling of bio-nano interactions of zero-valent silver nanoparticles.

Multifunctional Self‐Assembled Bio‐Interfacial Layers for High‐Performance Zinc Metal Anodes

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