Influência do Índice de Massa Corporal na Sobrevida de Mulheres com Diferentes Subtipos de Câncer de Mama: uma Revisão Integrativa

Pinheiro, Rosilene de Lima; Monteiro, Gina Torres Rego

doi:10.32635/2176-9745.rbc.2019v65n2.373

Cited by 4 publications

(3 citation statements)

References 48 publications

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“…In 2020, Motoki 15 , through a cross-sectional clinical study with 189 women, highlighted the profile in terms of BMI, which was 28.5±5.5 kg/m² (overweight). Furthermore, Pinheiro and Monteiro 16 , in an integrative literature review with six studies, identified worse survival in two patients with higher BMI, in agreement with the present study, in which the prevalence of overweight was 39.1% of the patients evaluated.…”

Section: Discussionsupporting

confidence: 92%

Five-year retrospective study of HER2+ breast cancer in a referral hospital in the state of Amazonas

Silva,

Pereira,

Moraes

et al. 2023

Mastology

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Introduction: Breast carcinoma is considered the most common malignancy in women, with a high incidence in Brazil and in the North region, surpassed only by non-melanoma skin cancer and cervical cancer. The HER2+ molecular subtype tends to grow and spread more quickly than other subtypes, resulting in the second worst outcome, behind only the triple-negative subtype. Methods: This was a retrospective, descriptive epidemiological study, using data from the medical records of 192 patients with HER2+ breast cancer treated at the Fundação Centro de Controle de Oncologia do Amazonas (FCECON), from 2014 to 2018. Results: The mean age of patients was 52±12 years. The predominant origin was Manaus. AM (53.1%). The most common education level was complete secondary education (36.5%) and the occupation was self-employed (37%). Most diagnoses were made in 2014 (23.4%). Regarding staging, the most common ones were stages IIIA and IIIB, both 20.83%. Concerning treatment, all patients (100%) underwent radiotherapy and chemotherapy, and surgery in 80.2%, including mastectomy (58.33%) and quadrantectomy (21.87%). Local recurrence and distant metastasis were both found in 7.3% of patients. With respect to the outcome, patients in follow-up predominated (53.6%), while mortality rate was 0.5%. Conclusions: The series demonstrated that patients with HER2 breast cancer present advanced staging and undergo neoadjuvant chemotherapy and surgery. The center in the present study is an institution that receives patients from several municipalities in the countryside of Amazonas and other states, and thus, many patients with advanced stages are cared for, since many such cities have no resources to perform mammography, compromising screening.

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Section: Discussionsupporting

confidence: 92%

Five-year retrospective study of HER2+ breast cancer in a referral hospital in the state of Amazonas

Silva,

Pereira,

Moraes

et al. 2023

Mastology

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“…Essa criação envolve representações e emoções sobre si e sobre os outros, que são construídas no decorrer da vida e de suas experiências. Logo, situações traumáticas como: alterações corporais em virtude da doença e tratamento, medo do futuro, mudanças de humor e percepção de outras pessoas causam alterações que podem ser permanentes ou momentâneas (26) . A pressão da sociedade por padrões, especialmente para as mulheres, é uma realidade profundamente enraizada em diversas culturas e contextos sociais.…”

Section: Discussionunclassified

Bem-estar funcional e físico e preocupações de sobreviventes de câncer de mama

De Carvalho Moreira,

Yuzo Okuma,

Domingues Mingueto

et al. 2023

Rev Bras Promoc Saúde

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Objetivos: Comparar os níveis de bem-estar funcional e físico e as preocupações específicas entre mulheres sobreviventes de câncer de mama. Método: Estudo transversal, correlacional, multicêntrico: uma instituição de saúde pública e outra suplementar, ambas no município de São Paulo, Brasil. A coleta de dados foi realizada no período de março a novembro de 2021, com mulheres diagnosticadas com câncer de mama de qualquer etiologia e estadiamento, livres da doença, com ou sem terapia endócrina. Foram utilizados Questionário Sociodemográfico e Clínico e o Functional Assessment of Cancer Therapy-Breast e a análise com estatística descritiva e analítica. Resultados: 90 mulheres participaram do estudo, com média de idade de 57,6 anos, a maioria diagnosticada entre 2017 e 2020. No sistema público, quanto à escolaridade, a maioria encontrava-se entre não alfabetizadas e com ensino médio incompleto, enquanto no grupo da saúde complementar, a maioria possuía ensino superior completo. No domínio preocupações adicionais-câncer de mama, o grupo público apresentou maior escore em relação à saúde complementar e, na soma dos dois grupos, a idade correlacionou-se positivamente e negativamente com o tempo de sobrevivência. Os escores de bem-estar funcional foram os mais baixos em ambos. Conclusão: O estudo destaca que mulheres sobreviventes de câncer de mama, independentemente do sistema de saúde, compartilham preocupações similares relacionadas à doença. Essas preocupações, especialmente evidentes em mulheres mais velhas e no SUS, têm um impacto significativo na qualidade de vida. É crucial que os planos de assistência considerem essas preocupações de forma individualizada, oferecendo suporte e educação após o tratamento.

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“…Breastfeeding is an action that should be promoted from the primary care, being a simple and low-cost measure that can reduce the probability of developing TNBC by up to 21% [43]. Although it is controversial whether obesity influences disease-free survival and overall survival, a normal BMI is recommended [44,45].…”

Section: Discussionmentioning

confidence: 99%

Atypical Presentation of Triple-Negative Breast Cancer

Garcia-Cahuich¹,

Rodríguez-Solis²,

García-Carrillo³

et al. 2021

Int J Cancer Clin Res

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CASE REpoRt ANd SYStEMAtiC REViEwCheck for updates one year, 2,261,419 million cases of cancer have been diagnosed, of which breast cancer represents 11.7% of all types of cancer with 684,996 deaths reported [1]. A patient suffering breast cancer has about 77 years of life expectancy and being diagnosed with an average of years of 52.5-years-old, being the majority diagnosed after 50-years-old, a 23% are found in those under 45-years-old [5,6].Only 10% of breast cancer cases have genetic background, being the majority, sporadic (90%) [5]. The definitive diagnostic is made by biopsy with positive results of malignancy classified by immunohistochemistry (IHC) depending by positivity of Estrogenic Receptors (ER), Progesterone Receptors (PR) and Epidermal growth factor receptor 2 (HER2) [4,6,7]. Immunohistochemistry classification is being classified by subtypes: Luminal A, Luminal B, HER2 positive and Triple-negative [7]. In Mexico, the incidence according to the IHC is of hormone receptors 60%, HER-2 positive 20.4% and triple-negative 23.1% [8].The Triple negative Breast Cancer (BCTN) it been defined as the absence of Estrogenic Receptors (ER), Progesterone Receptors (EP), Epidermal growth factor receptor 2 (HER2) [2,4,[8][9][10][11], and it conforms 10 to 20% of all cases of breast cancer [10,12,13]. It has been made a study by Acta Medica Grupo Angeles, in the Angeles Summary Introduction: Triple-Negative Breast Cancer (BCTN) has been defined as the absence of Estrogenic Receptors (ER), Progesterone Receptors (EP), Epidermal growth factor receptor 2 (HER2), and it conforms 10 to 20% of all cases of breast cancer.Case report: A 42-years-old female, debuting with abdominal pain, a 44 pounds of weight loss on the last 2 months and abdominal mass presence. A single complex looking nodule found in the left breast, which underwent a biopsy with results of triple negative breast adenocarcinoma, she had kidney failure, hypoglycemia and neurological impairment concluding in death.Discussion: Triple-Negative Breast Cancer occurs in young women, it has an aggressive development, it characterized by present brain metastasis giving to it an ominous prognostic.

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Influência do Índice de Massa Corporal na Sobrevida de Mulheres com Diferentes Subtipos de Câncer de Mama: uma Revisão Integrativa

Cited by 4 publications

References 48 publications

Five-year retrospective study of HER2+ breast cancer in a referral hospital in the state of Amazonas

Five-year retrospective study of HER2+ breast cancer in a referral hospital in the state of Amazonas

Bem-estar funcional e físico e preocupações de sobreviventes de câncer de mama

Atypical Presentation of Triple-Negative Breast Cancer

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