Influential Factors to Prolonged Tuberculosis Treatment Duration and Multidrug-resistant Tuberculosis Incidence

Choi, Young-Soon; Tae, Yoon-Hee; Kim, Jeeyoon

doi:10.21032/jhis.2016.41.3.344

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Not having sufficient healthcare services and corresponding high TB incidence risks, many regions are in the vicious cycle of TB in the study area [ 60 ]. Consequently, prolonged TB treatment and MDR (Multidrug-resistant) TB incidence risks are higher in these regions [ 61 ]. TB incidence driven by economic status and corresponding vicious cycle in the regions would widen TB incidence gap as the result of regional economic polarization in Korea.…”

Section: Resultsmentioning

confidence: 99%

Spatial pattern of tuberculosis (TB) and related socio-environmental factors in South Korea, 2008-2016

Kim

2021

PLoS ONE

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Tuberculosis (TB) incidence and corresponding mortality rates in S. Korea are unusual and unique compared to other economically developed countries. Korea has the highest TB incidence rate in Organization for Economic Co-operation and Development (OECD) countries. TB is known as a disease reflecting socio-economic and environmental conditions of a society. Besides, TB is an infectious disease spread through the air, naturally forming spatial dependence of its incidence. This study investigates TB incidences in Korea in socio-economic and environmental perspectives. Eigenvector spatial filtering applied accounts for spatial autocorrelation in the TB incidence, and Getis-Ord Gi* statistic tracks the changes of TB clusters at given time. The results show that population composition ratio, population growth rate, health insurance payment, and public health variables are significant throughout the study period. Environmental variables make minor effects on TB incidence. This study argues that unique demographic features of Korea are a potential threat to TB control in the future.

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Section: Resultsmentioning

confidence: 99%

Spatial pattern of tuberculosis (TB) and related socio-environmental factors in South Korea, 2008-2016

Kim

2021

PLoS ONE

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Change in Quality of Tuberculosis (TB) Care since National Quality Assessment Program of TB Healthcare Service

Jang¹,

Hwang²,

Chung-Hun³

et al. 2021

Qual Improv Health Care

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Purpose: This study aims to examine the quality of tuberculosis (TB) care after the 1<sup>st</sup> to 3<sup>rd</sup> national quality assessment (QA) program for TB healthcare service in Korea was conducted.Methods: We analyzed Health Insurance Review & Assessment Service (HIRA) claims data of new TB patients during the period of January to June from 2018-2020. The new TB patients were defined as TB patients reported to Korea Centers for Disease Control and Prevention Agency (KCDA). The unit of analysis was the patient. Chi-square tests were used to analyze the differences in indicator value according to the types of medical facilities. The QA indicators of TB care were divided into 3 areas consisting of the following 7 quality indicators: 4 indicators of diagnosis test (the rate of acid-fast bacilli smear, the rate of acid-fast bacilli culture, the rate of Mycobacterium tuberculosis-polymerase chain reaction, drug susceptibility test), 1 compliance of treatment guideline, and 2 indicators of care management of TB patients (encounter rate, day of therapy).Results: The QA program for TB care was conducted among 8,246 patients from 534 facilities in 2020. The value of the 7 quality indicators was shown to increase as a result of the QA program. The indicators of the diagnostic test were all higher than 95%, with the exception of the drug susceptibility test which was 84.8%. Both indicators for care management of TB patients were 88.5%.Conclusion: The quality of TB care has been improving with the implementation of the QA program. In order to continue to improve the quality of TB care, it will be necessary to disclose the results of the QA program in medical facilities in the future.

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Identifying Predictors of Unfavorable Treatment Outcomes in Tuberculosis Patients

Lee,

Myong,

Kim

et al. 2024

IJERPH

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Objectives: In South Korea, there has been a continuous decrease in the incidence of tuberculosis (TB) attributable to a national TB elimination program; however, TB still poses a significant socioeconomic burden. This study aimed to analyze factors associated with successful TB treatment and to identify refractory patient groups with unfavorable outcomes. Methods: We analyzed anonymized data on 89,150 patients with TB provided by the Korea Disease Control and Prevention Agency. Specifically, we collected independent variables, which were categorized as individual, regional, and medical facility factors. Individual factors included age, sex, nationality, TB type, drug-resistant status, category of TB, housing type, underlying disease status, number of referrals, and smoking status. Regional factors referred to the region where the TB case was reported. Medical facility factors included the first visit to a medical facility, categorized by hospital type and the distinction between private–public mix (PPM) and non-PPM depending on the presence or absence of dedicated TB nurses. These factors were analyzed in relation to treatment success to identify refractory patient groups with unfavorable outcomes. Results: Multivariable logistic regression analysis revealed the following significant factors associated with successful TB treatment: sex, nationality, status of drug-resistant TB, category of TB, number of referrals, region of TB registry, underlying diseases, and smoking status. Specifically, compared with their relevant counterparts, male patients had a lower rate of successful treatment (adjusted odds ratio [aOR]: 0.66, reference [Ref.]: women); Korean nationals had a higher rate of treatment success (aOR: 7.20, Ref. foreign residents in Korea); resistant TB was associated with a lower rate of treatment success (aOR: 0.35, Ref.: non-resistant TB status); newly treated patients had a higher rate of treatment success (aOR: 1.75, Ref.: retreatment patient); switching hospitals once (aOR: 1.78), never (aOR: 1.41), or twice (aOR: 1.37) was associated with increased treatment success (Ref.: three or more times); having zero (aOR: 1.45), one (aOR: 1.31), or two (aOR: 1.24) underlying diseases was associated with a higher rate of treatment success (Ref. three or more underlying diseases); and past smokers (aOR: 1.40) and non-smokers (aOR: 1.35) had a higher rate of treatment success (Ref.: current smokers). Conclusions: Our study identified several factors contributing to unfavorable treatment outcomes in tuberculosis patients, including male patients, foreign residents in Korea, drug-resistant TB, retreatment patients, frequent hospital switching, multiple underlying diseases, and current smoking status. These research findings could inform the development of efficient management strategies and policies for improving the treatment success rate among patients with TB.

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Influential Factors to Prolonged Tuberculosis Treatment Duration and Multidrug-resistant Tuberculosis Incidence

Cited by 3 publications

References 18 publications

Spatial pattern of tuberculosis (TB) and related socio-environmental factors in South Korea, 2008-2016

Spatial pattern of tuberculosis (TB) and related socio-environmental factors in South Korea, 2008-2016

Change in Quality of Tuberculosis (TB) Care since National Quality Assessment Program of TB Healthcare Service

Identifying Predictors of Unfavorable Treatment Outcomes in Tuberculosis Patients

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