2021
DOI: 10.21873/invivo.12690
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Infrared Spectroscopic Study and Mathematical Simulations of Carotid Atherosclerosis

Abstract: Background/Aim: The pathogenesis, treatment and prevention of atherosclerosis continue to be the subject of intensive research and study by the scientific community. Based on Fourier-transform infrared spectra and 3D-Doppler echogram, we attempted to develop a computational simulation model for predicting the association of atherosclerotic risk factors with pathogenic molecular structural changes. Materials and Methods: Atheromatic carotid arteries from 56 patients (60-85 years old) were used as samples. Color… Show more

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Cited by 3 publications
(2 citation statements)
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“…However, there is a recent report that infrared spectroscopy and mathematical simulation can be used to image disease in the carotid artery in vivo. 155 This might suggest that the application of artificial intelligence would render this an interesting future technology to detect subclinical atherosclerosis.…”
Section: Methodsmentioning
confidence: 99%
“…However, there is a recent report that infrared spectroscopy and mathematical simulation can be used to image disease in the carotid artery in vivo. 155 This might suggest that the application of artificial intelligence would render this an interesting future technology to detect subclinical atherosclerosis.…”
Section: Methodsmentioning
confidence: 99%
“…FT-IR spectroscopy does not require any special sample preparation, however, the technical analyst must be careful when selecting the tissue samples. It is significant to notice that in order to obtain high quality spectra the scientists must avoid receiving formalin fixed paraffin embedded tissues [30][31][32][33][34][35][36][37]. The paraffin's absorption bands overlap the bands arising from membrane lipids and phospholipids.…”
Section: Ft-ir Spectroscopymentioning
confidence: 99%