Inhibition of herpes simplex virus type 1 by aqueous extracts from shoots of Helichrysum aureonitens (Asteraceae)

Meyer, J.J.M.; Afolayan, A. J.; Taylor, Maureen B.; Engelbrecht, Louise

doi:10.1016/0378-8741(96)01387-6

Cited by 62 publications

(27 citation statements)

References 9 publications

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“…Hypoxis hemerocallidea (African potato) and Catharanthus roseus (Rosy Periwinkle) (Good, 1974;Goldblatt & Manning, 2000;Gurib-Fakim, 2006). As seen in other parts of Africa, it is, therefore, not surprising that TM also forms the backbone of rural healthcare in South Africa (McGaw et al, 2005) and an estimated 27 million of the population depend on TMs and traditional healers for some or all of their healthcare needs (Cunningham, 1993;Meyer et al, 1996;Mander, 1998;McGaw et al, 2005). Traditional medicine coexists with modern medicine (van Wyk & Gericke, 2000) and caters for the health needs of diverse local populations , and is most prevalent in more rural areas where western medicines are inaccessible due to unavailability and/or their comparably high cost.…”

Section: Introductionmentioning

confidence: 99%

Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Raji

Mugabo

Obikeze

2012

Journal of Ethnopharmacology

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Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats I. A. RAJITulbaghia violacea Harv. (Alliaceae) is a small bulbous herb which belongs to the family, Alliaceae, most commonly associated with onions and garlic. In South Africa (SA), this herb has been traditionally used in the treatment of various ailments, including fever, colds, asthma, paralysis, hypertension (HTN) and stomach problems. The aim of this study was to evaluate the effect of methanol leaf extracts (MLE) of T. violacea on the blood pressure (BP) and heart rate (HR) in anaesthetized male spontaneously hypertensive rats; and to find out the mechanism(s) by which it acts.The MLE of T. violacea (5 -150 mg/kg), angiotensin I (ang I, 3.1 -100 µg/kg), captopril (10 mg/kg), angiotensin II (ang II, 3.1 -50 µg/kg), losartan (30 mg/kg), phenylephrine T. violacea (60 mg/kg) and captopril (10 mg/kg) were injected intraperitoneally into iii some SHR for 21 days to investigate the chronic effect of these agents on plasma levels of aldosterone. The mean change, the mean of the individual percentage changes and the percentage difference (in mean) observed with each intervention was calculated and statistically analyzed using the Student's t test for significant difference (p < 0.05). The Microsoft Excel software was used for statistical analysis.T. violacea significantly (p < 0.05) reduced the systolic, diastolic, and mean arterial BP;and HR dose-dependently. In a dose-dependent manner, ang I, ang II, phenylephrine significantly (p < 0.05) increased the BP, while propranolol, muscarine and atropine reduced the BP. The increases in BP due to dobutamine were not dose-dependent. In a dose dependent manner, phenylephrine and propranolol reduced the HR, while dobutamine increased the HR. The effect of ang I, ang II, muscarine and atropine on HR were not dose-dependent; with both increases as well as decreases observed with ang I, and II and atropine, while decreases were seen with muscarine. Captopril produced significant (p < 0.05) reduction in BP which were not associated with any change in HR.The co-infusion of ang I with the MLE produced significant (p < 0.05) reduction in BP, which were not associated with significant changes in HR. The co-infusion of ang II with the MLE did not produce any significant changes in BP or HR when compared to the infusion of the standard drug alone. The co-infusion of phenylephrine with the MLE did

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Section: Introductionmentioning

confidence: 99%

Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Raji

Mugabo

Obikeze

2012

Journal of Ethnopharmacology

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“…These plant extracts were also used to cure urinary tract infections, cervicitis vaginitis, and gastrointestinal disorders 20 and skin infections such as herpes simplex virus type-1 21 . Its leaf is traditionally known to be useful for the treatment of various diseases like bad breath, boils and abscesses, conjunctivitis, constipation, headache, hysteria, itches, mastitis, mastoiditis, leucorrhoea, ringworm, swelling of gum, rheumatism, abrasion, cuts and injuries etc.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Ethanol Extract of Betel Leaf (Piper betle L.) Against Some Food Borne Pathogens

Hoque

Rattila

Shishir

et al. 2012

Bangla. J. Microbiol.

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“…More than 50% of all modern drugs in clinical use are of natural products, many of which have the ability to control cancer cells. [13] According to the estimates of the WHO, more than 80% of people in developing countries depend on traditional medicine for their primary health needs. A recent survey shows that more than 60% of cancer patients use vitamins or herbs as therapy.…”

Section: Role Of Herbal Medicine In the Treatment Of Cancermentioning

confidence: 99%

Need of an Ancient Roots to Modern Medicine in the Treatment of Cancer- A review

Gunjan

Naidu²,

Marzo³

et al. 2017

ijpm

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A b s t r a c tThe already available expensive conventional therapies for cancer like chemotherapy and radiotherapy have a number of side effects such as myelosuppression and neurological, cardiac, pulmonary, and renal toxicity, which pose serious harm to the quality of there is a need to develop treatment options that include more potent and less toxic anticancer drugs as compared to existing drugs. and vegetables because of phytochemical compounds ex activity of antioxidant and free radicals which in turn showing anti semi agents are primarily used in com treatment of a variety of cancers. VLB is used for the treatment of leukaemia, lymphomas, advanced testicular cancer, breast and lung cancers, and Kaposi's sarcoma, and VCR, in addition to the treat acute lymphocytic leukaemia in childhood. VRLB has shown activity against non lung cancer and advanced breast cancer. based, natural process in order to stop the growth of cancer cells. This approach can limit the damage to normal cells and the accompanying side effects caused by conventional chemot agents. drug development. The current findings and known anticancer agents from natural sources are discussed, and recent therapeutic advances in this field

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Inhibition of herpes simplex virus type 1 by aqueous extracts from shoots of Helichrysum aureonitens (Asteraceae)

Cited by 62 publications

References 9 publications

Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Antibacterial Activity of Ethanol Extract of Betel Leaf (Piper betle L.) Against Some Food Borne Pathogens

Need of an Ancient Roots to Modern Medicine in the Treatment of Cancer- A review

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