Inkjet-Printed Monolayers as Platforms for Tethered Polymers

Sankhe, Amit Y.; Booth, Brandon D.; Wiker, Nathan J.; Kilbey, S. Michael

doi:10.1021/la0475472

Cited by 31 publications

(34 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…53,54 Some of these surfaces have been used to study cell growth. Other techniques have been used to gradually immobilize biomolecules, such as proteins, on surfaces, for example, microfluidics, 55-57 covalent coupling to an alkanethiol gradient, 58,59 covalent coupling by laser irradiation, 60 the use of stamping techniques and electrophoretics, 61 ink-jet printing, 62,63 drainage, 64 or by controlling the adsorption kinetics. 65 In this study we present the generation and characterization of PLL-g-PEG gradients prepared by means of an immersion process originally developed for alkanethiols ͓Fig.…”

Section: Introductionmentioning

confidence: 99%

Poly(l-lysine)-grafted-poly(ethylene glycol)-based surface-chemical gradients. Preparation, characterization, and first applications

et al. 2006

View full text Add to dashboard Cite

A simple dipping process has been used to prepare PEGylated surface gradients from the polycationic polymer poly(l-lysine), grafted with poly(ethylene glycol) (PLL-g-PEG), on metal oxide substrates, such as TiO2 and Nb2O5. PLL-g-PEG coverage gradients were prepared during an initial, controlled immersion and characterized with variable angle spectroscopic ellipsometry and x-ray photoelectron spectroscopy. Gradients with a linear change in thickness and coverage were generated by the use of an immersion program based on an exponential function. These single-component gradients were used to study the adsorption of proteins of different sizes and shapes, namely, albumin, immunoglobulin G, and fibrinogen. The authors have shown that the density and size of defects in the PLL-g-PEG adlayer determine the amount of protein that is adsorbed at a certain adlayer thickness. In a second step, single-component gradients of functionalized PLL-g-PEG were backfilled with nonfunctionalized PLL-g-PEG to generate two-component gradients containing functional groups, such as biotin, in a protein-resistant background. Such gradients were combined with a patterning technique to generate individually addressable spots on a gradient surface. The surfaces generated in this way show promise as a useful and versatile biochemical screening tool and could readily be incorporated into a method for studying the behavior of cells on functionalized surfaces.

show abstract

Section: Introductionmentioning

confidence: 99%

Poly(l-lysine)-grafted-poly(ethylene glycol)-based surface-chemical gradients. Preparation, characterization, and first applications

et al. 2006

View full text Add to dashboard Cite

show abstract

“…We envision that with more advanced patterning techniques and materials design, numerous polymer@graphene 2D objects with different functionalities will be developed in the near future. 21,26,27,[33][34][35][36] Polymer@graphene 2D objects T Gao et al…”

Section: Discussionmentioning

confidence: 99%

Transferable, transparent and functional polymer@graphene 2D objects

Gao

Liu

et al. 2014

NPG Asia Mater

View full text Add to dashboard Cite

Compared with inorganic two-dimensional (2D) materials, such as graphene and transition metal dichalcogenides, organic 2D materials are believed to possess more interesting chemical and biological properties for certain applications, such as separation membranes, smart surfaces, sensors, catalysis and drug delivery. However, the study of organic 2D materials is largely hindered because of the lack of effective methods to produce them. This paper presents a new type of organic 2D material, namely 'polymer@graphene 2D objects', that can be synthesized via a simple and scalable chemistry. Polymer@graphene 2D objects are made of functional polymer brushes that tether one end of the polymer chain on the surface of graphene sheets via non-covalent p-p stacking interactions. These materials are transparent, freestanding, lightweight, flexible, transferable to various substrates with good stability and are patternable into different structures. Their functionality can be tailored by changing the polymer brushes that are immobilized. In this paper, we demonstrate the applications of these 2D objects in the smart control of surface wettability and DNA biosensors. INTRODUCTION Two-dimensional (2D) inorganic materials including graphene 1-3 and various transition metal dichalcogenides 4-6 have received tremendous attention in the past decade because of their unique properties and wide applications in optics and electronics. These remarkable phenomena have recently attracted research interest in 2D organic materials, including 2D polymers 7-10 and quasi-2D polymers. [11][12][13][14][15] The focus has mainly been on their chemical and biological properties and their applications as separation membranes, smart surfaces and sensors, and for catalysis and drug delivery. However, the 2D polymers reported to date are only limited to very specific building blocks and microscale sizes because of the lack of robust methods to produce them. On the other hand, the preparation of quasi-2D polymers either requires the undesirable crosslinking of the materials, using expensive and opaque novel metal supports, or high-energy electron beams. 16,17 Therefore, the investigation of the fundamental properties as well as practical applications of these organic 2D materials have remained largely hindered.In this paper, we report the development of a new type of functional organic 2D material, namely 'polymer@graphene 2D objects' , which are prepared in a cost-effective and high-throughput manner. Polymer@graphene 2D objects are made of functional

show abstract

“…57 Brush-like polymer gradients were also generated from gradients of alkanethiol initiator sites applied by ink-jet printing. 50 Functionality gradients prepared by corona treatment were also further used to graft polymer chains. The oxygenated species were used as grafting sites for various polymers, such as PEG 58 or others.…”

Section: Polymer-based Techniquesmentioning

confidence: 99%

“…The attachment and movement of cells depends strongly on the surface concentration and the confirmation of adsorbed proteins, and thus it is useful to study this behaviour in a high-throughput manner. Proteins have been covalently coupled to alkanethiol gradients by, for example, an amine group 37,81 or by laser irradiation 78 and they have been ink-jet printed 50 or stamped. 82 Other groups have controlled the adsorption kinetics by changing the contact time of a substrate with a protein solution.…”

Section: 79mentioning

confidence: 99%

Surface-chemical and -morphological gradients

2008

View full text Add to dashboard Cite

Surface gradients of chemistry or morphology represent powerful tools for the high-throughput investigation of interfacial phenomena in the areas of physics, chemistry, materials science and biology. A wide variety of methods for the fabrication of such gradients has been developed in recent years, relying on principles ranging from diffusion to time-dependent irradiation in order to achieve a gradual change of a particular parameter across a surface. In this review we have endeavoured to cover the principal fabrication approaches for surface-chemical and surface-morphological gradients that have been described in the literature, and to provide examples of their applications in a variety of different fields.

show abstract

Inkjet-Printed Monolayers as Platforms for Tethered Polymers

Cited by 31 publications

References 17 publications

Poly(l-lysine)-grafted-poly(ethylene glycol)-based surface-chemical gradients. Preparation, characterization, and first applications

Poly(l-lysine)-grafted-poly(ethylene glycol)-based surface-chemical gradients. Preparation, characterization, and first applications

Transferable, transparent and functional polymer@graphene 2D objects

Surface-chemical and -morphological gradients

Contact Info

Product

Resources

About