Inner ear fluid‐attenuated inversion recovery MRI signal intensity in dogs with vestibular disease

Castillo, Gibrann; Parmentier, Thomas; Monteith, Gabrielle; Gaitero, Luís

doi:10.1111/vru.12876

Cited by 11 publications

(15 citation statements)

References 23 publications

(46 reference statements)

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“…Imaging findings in large felids with otitis media/interna were identical to those reported in domestic dogs and cats and included abnormal material within the tympanic bulla, bulla wall thickening, and alteration in normal fluid signal from the inner ear (40,41).…”

Section: Discussionsupporting

confidence: 53%

Magnetic Resonance Imaging in 50 Captive Non-domestic Felids - Technique and Imaging Diagnoses

et al. 2022

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Magnetic resonance imaging (MRI) is the recognized gold standard for diagnostic imaging of the central nervous system in human and veterinary patients. Information on the use of this modality and possible imaging abnormalities in captive non-domestic felids is currently limited to individual case reports or small case series. This retrospective study provides information on technique and imaging findings in a cohort of cases undergoing MRI at an academic Veterinary Medical Center. The University of Tennessee College of Veterinary Medicine MRI database was searched for non-domestic felids undergoing MRI of the brain or spine from 2008 to 2021. Medical record data were recorded, and MRI studies were reviewed. Fifty animals met the inclusion criteria. The most common brain diseases were Chiari-like malformation (n = 8) and inflammatory conditions (n = 8). Other abnormalities included pituitary lesions (n = 5), brain atrophy (n = 2), and one each of metabolic and traumatic conditions. Fourteen animals had a normal brain MRI study. The most common spinal abnormality was intervertebral disc disease (n = 7). Other disorders included vertebral dysplasia (n = 2), presumptive ischemic myelopathy (n = 1), subdural ossification causing spinal cord compression (n = 1), and multiple myeloma (n = 1). Spinal cord swelling of undetermined cause was suspected in two animals, and seven patients had a normal MRI study of the spine. MRI is a valuable tool in the diagnostic workup of non-domestic felids with presumptive neurologic disease.

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Section: Discussionsupporting

confidence: 53%

Magnetic Resonance Imaging in 50 Captive Non-domestic Felids - Technique and Imaging Diagnoses

et al. 2022

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“…The pathological mechanism of ISSNHL is currently not clear, which brings great challenges to the studies of etiology and therapeutics of ISSNHL . Recent studies have found that modern magnetic resonance imaging technology can detect abnormal changes in the labyrinth of the inner ear . Accumulating studies have confirmed that 3.0T MRI, especially the 3D-FLAIR sequence, has good sensitivity and specificity to the alterations in ISSNHL inner ear signals. , The application of 3D-FLAIR MRI can assist clinicians to find different pathological changes in the inner ear on time.…”

Section: Discussionmentioning

confidence: 99%

Clinical Value of 3D-FLAIR MRI in Idiopathic Sudden Sensorineural Hearing Loss

Wang

Hu²,

Wang

et al. 2021

ACS Chem. Neurosci.

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Background: Three-dimensional fluid-attenuated inversion recovery sequence magnetic resonance imaging (3D-FLAIR MRI) has been used in the diagnosis of inner ear diseases. However, the relevance of 3D-FLAIR MRI appearances with multiple features and prognosis of patients with idiopathic sudden sensorineural hearing loss (ISSNHL) remains unclear. Methods: This study was a retrospective trial. We recruited 1300 patients with unilateral ISSNHL hospitalized from May 2017 to January 2019. They were divided into four groups according to their 3D-FLAIR MRI appearances: normal (n = 739), inner ear hemorrhage (n = 218), increased protein content (n = 288), and blood–labyrinth barrier damage (n = 55). The correlation between 3D-FLAIR MRI appearances and the degree or type of deafness of the participants was analyzed. Results: There was a statistical difference in the deafness side (p < 0.001) and vestibular dysfunction (p < 0.001) among the four groups. There was a statistical difference in the duration of treatment (p < 0.001) and the incidence of dizziness or vertigo (p < 0.001) for patients among these groups. The degree of deafness in the patients in the inner ear hemorrhage group was significantly more severe than that of the patients in the other three groups (p < 0.001). Conclusion: 3D-FLAIR MRI appearances were correlated with the prognosis of patients with ISSNHL.

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“…A laminated appearance of the mucosa of the tympanic bulla on T2W images has also been described (17). A reduced signal intensity on T2W or an increase signal intensity on FLAIR images from the intralabyrinthine fluid are MRI finding suggestive of otitis interna (14,16,18). Due to anatomical proximity, intracranial extension of OMI can lead to a meningeal enhancement (MgE) on MRI after intravenous administration of paramagnetic contrast medium (19).…”

Section: Introductionmentioning

confidence: 92%

“…14,15 A marked hyperintensity compared with adjacent structures is present on T2W images, while suppression is visible in FLAIR. 14,15 Postcontrast T1-weighted (T1W) images may show an abnormality consistent with inflammatory changes in the inner ear. 1 Typical changes raising the suspicion of OMI include isointense material in the bulla on T1W images and hyperintense on T2W images.…”

Section: Introductionmentioning

confidence: 99%

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Otitis media and interna with or without polyps in cats: association between meningeal enhancement on postcontrast MRI, cerebrospinal fluid abnormalities, and clinician treatment choice and outcome

Dutil

Guevar

Schweizer

et al. 2022

Journal of Feline Medicine and Surgery

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Objectives The aim of this study was to evaluate the association between meningeal enhancement (MgE) and cerebrospinal fluid (CSF) analysis results, their individual association with bacteriology results from affected ear samples and whether these test results influenced clinicians’ therapeutic choice in cats with otitis media and interna (OMI). Methods This was a multicentre retrospective study carried out over an 8-year period. Cats diagnosed with OMI, with or without a nasopharyngeal polyp, leading to peripheral vestibular signs were included. Only cats for which MRI with postcontrast T1-weighted sequences and CSF analyses available were included. Cats with intra-axial MRI lesions or empyema were excluded. Results Fifty-eight cats met the inclusion criteria. MgE was reported in 26/58 cases, of which nine had an abnormal CSF result (increased total nucleated cell count [TNCC] or total protein); 32/58 cases had no MgE, of which 10 showed abnormal CSF results. There was no association between bacteriology results (external ear canal or bulla) and MgE or abnormal CSF results. CSF abnormalities were statistically significantly more common in acute cases (n = 16/37) than in chronic cases (n = 3/21; Fischer’s test P = 0.04). Prednisolone was prescribed in 10/16 cases with increased TNCC. Among the 42 cases with normal TNCC, 15 received prednisolone and 13 received non-steroidal anti-inflammatory drugs. Various antimicrobial drugs were prescribed in 53/58 cats. Duration of antimicrobial treatment was similar, regardless of positive bacterial culture (5.58 vs 4.22 weeks), abnormal CSF (5.83 vs 4.76 weeks) or MgE (5.33 vs 4.90 weeks). Conclusions and relevance No association was found between the CSF and MgE results. Furthermore, no association was found between MgE, CSF or bacteriology findings. In addition, abnormal CSF results might lead the clinician to treat with corticosteroids, but they did not have any impact on duration of antimicrobial treatment. CSF abnormalities were seen significantly less frequently in chronic cases. The outcome tended to be poorer when MgE was detected on MRI.

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Inner ear fluid‐attenuated inversion recovery MRI signal intensity in dogs with vestibular disease

Cited by 11 publications

References 23 publications

Magnetic Resonance Imaging in 50 Captive Non-domestic Felids - Technique and Imaging Diagnoses

Magnetic Resonance Imaging in 50 Captive Non-domestic Felids - Technique and Imaging Diagnoses

Clinical Value of 3D-FLAIR MRI in Idiopathic Sudden Sensorineural Hearing Loss

Otitis media and interna with or without polyps in cats: association between meningeal enhancement on postcontrast MRI, cerebrospinal fluid abnormalities, and clinician treatment choice and outcome

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