Inorganic nitrate supplementation and exercise. Is skeletal muscle involved in the heavy lifting?

Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension

“…Recognizing the individual variation in some of our data, we might have been able to detect subtle differences between the groups with a larger sample size. Furthermore, acknowledging emerging data suggesting differential responses to nitrate in men as compared with women, 47,48 a larger number of both male and female study participants may have enabled us to assess if there is any evidence of sex-related effects. Considering that we pre-screened 409 volunteers and that 389 of them were excluded during the screening procedures, mainly due to use of medications specified as exclusion criteria, this made recruiting eligible participants difficult.…”