2024
DOI: 10.1038/s41598-024-70642-w
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Insights into aging mechanisms from comparative genomics in orange and silver roughies

Dido Carrero,
Maria Pascual-Torner,
Diana Álvarez-Puente
et al.

Abstract: The demersal fish orange roughy (Hoplostethus atlanticus) can live for up to 250 years, twenty times more than its congener silver roughy (Hoplostethus mediterraneus). Studies of Hoplostethus have focused mainly on its ecology and conservation due to its vulnerability to commercial fishing. In this work, we present the de novo genomes of orange and silver roughies and explore the genomic mechanisms that could contribute to such differential longevities. Using comparative genomics on a list of more than 400 gen… Show more

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