Instability of IGF–IGFBP complex as a cause of the different performance of serum and EDTA-plasma after storage: EDTA-plasma is preferable for evaluating bioactive IGF especially in the mouse

A novel immunoassay for quantitative drug abuse screening in serum

“…Long-term storage and sample handling could affect the stability of serum compounds (ElMaouche et al, 2016;Rakow et al, 2014;Setoyama et al, 2015). Therefore, it is possible that various metabolites or degradation products were present, which was not observed within the measurements.…”