Integrated approach to the management of patients having cicatricial deformity of the uterine cervix

Abstract

Introduction: Cicatricial deformity of the uterine cervix is a relevant and understudied problem in medicine. It is important to conduct preoperative preparation aimed at creating a favorable background for operative treatment as well as to conduct post-operative treatment for improving and accelerating the reparative processes. Objective: Improving the results of surgical treatment of cicatricial deformity of the uterine cervix with the help of preoperative preparation and evaluating the efficiency of application of the Flamena gel complex in the post-operative period. Method: There were 30 patients having cicatricial deformity of the uterine cervix aged 25 to 45 under observation. With all patients, the clinical, laboratory and instrumental examination was conducted which included: microscopic examination of the intensity of leukocytosis in the vaginal and cervical secretion, cytological examination, bacteriological inoculation from the cervical canal, the PCR method test for sexually transmitted infections (the STIs), detection of the human papillomavirus, the content of immunoglobulines (IgA, IgG, IgM) in the venous blood serum and in the mucous secretion of the cervical canal, colposcopy, ultrasonography, and histological examination of the uterine cervix. Results: After normalizing the biocenosis of the vagina, the Superlimf 25 units immunomodulating agent was prescribed to all patients, as another preoperative preparation stage. Then surgical treatment was performed. In the post-operative period, the Flamena gel complex was prescribed. The combined therapy contributed to improving the results of the surgical treatment. Conclusion: The algorithm suggested by the authors which includes preoperative preparation, surgical treatment and post-operative care can be used as an integrated approach to the management of patients having cicatricial deformity of the uterine cervix.