Integrated flexible handheld probe for imaging and evaluation of iridocorneal angle

Abstract

An imaging probe is designed and developed by integrating a miniaturized charge-coupled diode camera and light-emitting diode light source, which enables evaluation of the iridocorneal region inside the eye. The efficiency of the prototype probe instrument is illustrated initially by using not only eye models, but also samples such as pig eye. The proposed methodology and developed scheme are expected to find potential application in iridocorneal angle documentation, glaucoma diagnosis, and follow-up management procedures.

High resolution iridocorneal angle imaging system by axicon lens assisted gonioscopy

“…Further, we also compared the results with an integrated flexible handheld wide angle probe which was recently developed in our research centre for imaging and documenting ICA 17 ( Fig. 7g,h ).…”

“…The flexible handheld probe has an imaging sensor located at the central axis of the probe and has a variable resolution at different depths which is optimized for recording the ICA of the eye 17 . The imaging probe was placed near the limbal region of the porcine cornea to image the opposite ICA through vidisic gel.…”

“…The anterior curvature and posterior surface of the cornea can be analyzed by Orbscan scanning-slit topography 15 . However, direct visualization of ICA is not possible using either the Pentacam or Orbscan scanning slit topography 17 . UBM can be used for direct angle visualization, however, it is a contact procedure, expensive and has not been established as a common clinical procedure 2 .…”

Chemical and biochemical sensing applications of microstructured optical fiber‐based systems

“…Solutions with the sample were introduced by capillary action. The fluorescence response was found to be more efficient when using water as medium, as well as the structure with central wavelength of 1060 nm . The same authors also proposed an integrated HC‐PCF transverse optical trapping system for optical manipulation and detection.…”

Preclinical imaging of iridocorneal angle and fundus using a modified integrated flexible handheld probe

“…17 Our group has worked on many optical instrumentation projects for biomedical imaging applications. 18,19 We have recently demonstrated a miniaturized integrated charge-coupled device (CCD) camera and light-emitting diode (LED) light probe imaging system to image and evaluate the iridocorneal angle of the porcine eye. This paper in this context discusses the modified probe system which can record, capture, and display images of the iridocorneal angle region and fundus using visible and near-infrared sources.…”