Integrated laboratory coagulation tests in hypercoagulation diagnosis and thrombosis risk assessment. Part II. The sensitivity of integral tests to hypercoagulable states

Lipets, Elena N.; Ataullakhanov, Fazly I.; Panteleev, Mikhail A.

doi:10.17650/1818-8346-2015-10-3-78-91

Onkogematologiâ

2015

DOI: 10.17650/1818-8346-2015-10-3-78-91

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Integrated laboratory coagulation tests in hypercoagulation diagnosis and thrombosis risk assessment. Part II. The sensitivity of integral tests to hypercoagulable states

Elena N. Lipets¹,

Fazly I. Ataullakhanov²,

Mikhail A. Panteleev³

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2023

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Cited by 1 publication

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Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

Varavin,

Salukhov,

Kryukov

et al. 2023

Medicinskij sovet

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Aim. To study various modes of anticoagulant therapy for the prevention of venous thrombosis of the lower extremities in the wounded after surgery using the parameters of the plasma hemostasis system and the Thrombodynamics test.Materials and methods. A prospective study was conducted, which included 90 wounded with mine-explosive/gunshot injury receiving anticoagulant therapy in preventive doses. The studies were carried out on the equipment of the Thrombodynamics recorder (HemaCor, Moscow). The patients were divided into 3 groups: 1 group, which included 30 patients taking rivaroxaban at a dose of 10 mg/day, 2 group of 30 patients receiving enoxaparin sodium at a dose of 40 mg once a day, 3 group consisting of 30 patients receiving enoxaparin sodium 40 mg 2 times a day. In the dynamics of treatment, the parameters of the plasma hemostasis system and the parameters of the Thrombodynamics test were evaluated.Results. It was revealed that during preventive anticoagulant therapy, there were no significant differences in the standard parameters of the coagulogram, when studying the parameters of the Thrombodynamics test, significant differences were observed between groups 1 and 3 in values (V/VSt, Vi, Tlag, СS), between group 2 and 3 in parameter (V/VSt, Vi, Tlag, СS), between group 1 and group 2 in the value of D. A statistically significant relationship was found between the Thrombodynamics parameter D and the indicators of TV, prothrombin by Quick, and fibrinogen content.Conclusion. The Thrombodynamics test can be used as a potential tool for a personalized approach to monitoring the hemostasis system in the wounded.

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Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

Varavin,

Salukhov,

Kryukov

et al. 2023

Medicinskij sovet

View full text Add to dashboard Cite

show abstract

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Integrated laboratory coagulation tests in hypercoagulation diagnosis and thrombosis risk assessment. Part II. The sensitivity of integral tests to hypercoagulable states

Cited by 1 publication

References 73 publications

Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

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